Peroxiredoxin 1 antibody

Catalog No. ABIN7207883

This Mouse Monoclonal antibody specifically detects Peroxiredoxin 1 in WB, IHC and IF. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for Peroxiredoxin 1 antibody (ABIN7207883)

Target: Peroxiredoxin 1 (PRDX1)

Reactivity: Human, Mouse, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This Peroxiredoxin 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-Peroxiredoxin 1 Antibody

Purpose: Mouse Anti-Peroxiredoxin 1 Monoclonal Antibody

Specificity: The antibody detects endogenous Peroxiredoxin 1 protein.

Purification: The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

Immunogen: Recombinant Protein

Isotype: IgG1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:1000-3000,IF 1:100-200,IHC 1:50-300

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.5 % BSA, 0.02 % sodium azide as Preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Peroxiredoxin 1

Target: Peroxiredoxin 1 (PRDX1)

Alternative Name: Peroxiredoxin 1

Background: PRDX1, PAGA, PAGB, TDPX2, Peroxiredoxin-1, Natural killer cell-enhancing factor A, NKEF-A, Proliferation-associated gene protein, PAG, Thioredoxin peroxidase 2, Thioredoxin-dependent peroxide reductase 2PRDX1 encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. Peroxiredoxin 1 may play an antioxidant protective role in cells, and may contribute to the antiviral activity of CD8 (+) T-cells. Peroxiredoxin 1 may have a proliferative effect and play a role in cancer development or progression. Four transcript variants encoding the same protein have been identified for PRDX1.

Molecular Weight: 21kD

Gene ID: 5052

UniProt: Q06830

Pathways: p53 Signaling, EGFR Signaling Pathway, CXCR4-mediated Signaling Events