ABI1 antibody (N-Term)

Catalog No. ABIN453492

The Rabbit Polyclonal anti-ABI1 antibody (ABIN453492) specifically detects ABI1 in WB, IF, IHC (p), FACS and EIA. The antibody is reactive with Human samples.

Quick Overview for ABI1 antibody (N-Term) (ABIN453492)

Target: ABI1 (Abl-Interactor 1 (ABI1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ABI1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

Product Details anti-ABI1 Antibody

Binding Specificity: AA 87-117, N-Term

Specificity: This antibody reacts to Abl interactor 1.

Purification: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 87~117 amino acids from the N-terminal region of Human ABI1

Application Details

Application Notes: ELISA: 1/1,000. Western blotting: 1/100 - 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for ABI1

Target: ABI1 (Abl-Interactor 1 (ABI1))

Alternative Name: ABI1 / SSH3BP1

Background: ABI1 has been found to form a complex with EPS8 and SOS1, and is thought to be involved in the transduction of signals from Ras to Rac. In addition, this protein may play a role in the regulation of EGF-induced Erk pathway activation as well as cytoskeletal reorganization and EGFR signaling.Synonyms: Abelson interactor 1, Abi-1, Abl interactor 1, Abl-binding protein 4, AblBP4, Eps8 SH3 domain-binding protein, Nap1-binding protein, Spectrin SH3 domain-binding protein 1, Spectrin binding protein, e3B1

Gene ID: 10006

NCBI Accession: NP_001012768

UniProt: Q8IZP0

Pathways: RTK Signaling, Response to Water Deprivation, ER-Nucleus Signaling