Suppressor of Cytokine Signaling 1 (SOCS1) (N-Term) antibody

Details for Product No. ABIN453835
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Antigen
Synonyms socs1, zgc:91868, jab, cis1, ssi1, tip3, cish1, ssi-1, socs-1, SOCS1, LOC100228306, socs1b, CIS1, CISH1, JAB, SOCS-1, SSI-1, SSI1, TIP3, Cish1, Cish7, Socs-1
Epitope
N-Term
(30), (16), (5), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Reactivity
Human, Mouse (Murine)
(98), (49), (42), (16), (13), (5), (1), (1), (1)
Host
Rabbit
(94), (8), (7)
Clonality
Polyclonal
Conjugate
Un-conjugated
(3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
(95), (38), (24), (13), (10), (10), (8), (7), (6), (4), (3), (3), (2)
Pubmed 2 references available
Quantity 0.4 mL
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Catalog No. ABIN453835
357.50 $
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Immunogen KLH conjugated synthetic peptide selected from the N-terminal region of human SOCS1
Specificity This antibody reacts to SOCS1.
Purification Saturated Ammonium Sulfate (SAS) precipitation
Alternative Name SOCS1
Background SOCS1 is a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling(SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling.Synonyms: JAB, JAK-binding protein, SOCS-1, SSI-1, SSI1, STAT-induced STAT inhibitor 1, Suppressor of cytokine signaling 1, TIP-3, TIP3, Tec-interacting protein 3
Gene ID 8651
NCBI Accession NP_003736
UniProt O15524
Research Area Chromatin and Nuclear Signaling, Signaling, Cytokines
Application Notes ELISA: 1/1,000. Western blotting: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Background publications Starr, Willson, Viney et al.: "A family of cytokine-inducible inhibitors of signalling." in: Nature, Vol. 387, Issue 6636, pp. 917-21, 1997 (PubMed).

Minamoto, Ikegame, Ueno et al.: "Cloning and functional analysis of new members of STAT induced STAT inhibitor (SSI) family: SSI-2 and SSI-3." in: Biochemical and biophysical research communications, Vol. 237, Issue 1, pp. 79-83, 1997 (PubMed).

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