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Antibodies
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anti-Platelet-Derived Growth Factor Receptor, alpha Polypeptide (PDGFRA) antibody
Platelet-Derived Growth Factor Receptor, alpha Polypeptide (PDGFRA) antibody
| Antigen |
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| Synonyms |
CD140A, PDGFR2, MGC74795, RHEPDGFRA, PDGFRA |
| Clonality |
Monoclonal (16A1) |
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Host
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Reactivity
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Application
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 Alternatives Flow Cytometry (FACS), Immunocytochemistry (ICC)
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| Catalog no. |
ABIN457411 |
| Quantity |
0.1 mg (1 mg/ml) |
| Price |
286.00 $ Plus shipping costs $35.00
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| Shipping to |
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| Availability |
Ships within 3 to 5 Business Days |
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Alternative name
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CD140a / PDGF-RA
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Immunogen
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CD140a-transfected NIH 3T3 cells
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Format
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Purified
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Isotype
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IgG1 (Matching secondary antibodies)
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Clone
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16A1
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Description
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CD140a / PDGF-RA (platelet-derived growth factor receptor alpha) is a cell surface receptorfor members of platelet-derived growth factor family, whose intracellular part contains atyrosine kinase domain. CD140a forms homodimers, or heterodimerizes with CD140b /PDGF-RB. Whereas CD140b induces in different cell types their proliferation and migration,the role of CD140a is more controversial, with pro-proliferative or anti-proliferative effects.CD140a has early developmental functions, mediates mesodermal cell migration, and lateracts in signaling associated in epithelial-mesenchymal interactions.
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Specificity
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The mouse monoclonal antibody 16A1 recognizes CD140a / PDGF-RA, the 170 kDa alphachain of platelet-derived growth factor receptor, which is widely expressed on a variety ofmesenchymal-derived cells and plays pro-proliferative or anti-proliferative roles in varioustumours.HLDA VI., WS Code E022
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Application Notes
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Flow Cytometry: Recommended dilution: 2 µg/ml
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Concentration
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1 mg/ml
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Purity
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> 95% (by SDS-PAGE)
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Purification
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Purified from ascites by protein-A affinity chromatography.
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Buffer
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Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
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Storage
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Store at 2-8 o C. Do not use after expiration date stamped on vial label. For long-term storage aliquot and store at -20 o C. Avoid freeze/thaw cycles.
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Restrictions
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For Research Use only
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Alternatives for antigen "Platelet-Derived Growth Factor Receptor, alpha Polypeptide (PDGFRA)", type "Antibodies"
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Hosts
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Rabbit (20), Mouse (4), Rat (1)
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Reactivities
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Human (24), Mouse (Murine) (5), Rat (Rattus) (3)
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Applications
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ELISA (12), Western Blotting (WB) (12), Enzyme Immunoassay (EIA) (9), Immunohistochemistry (IHC) (7), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (4), Flow Cytometry (FACS) (2), Functional Studies (Func) (1), Immunofluorescence (IF) (1)
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Conjugates
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APC (1), Biotin (1), PE (1)
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Epitopes
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C-Term (3), Y1018 (1), Y572 (1), Y574 (1), Y720 (1), Y754 (1), Y762 (1), Y768 (1), Y988 (1), pTyr1018 (1), pTyr572 (1), pTyr574 (1), pTyr754 (1), pTyr762 (1), pTyr849 (1), pTyr988 (1)
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