PAK1/2/3 antibody (pThr423)

Catalog No. ABIN481976

The Rabbit Polyclonal anti-PAK1/2/3 antibody is suitable to detect PAK1/2/3 in samples from Human, Rat and Mouse. It has been validated for IHC and ELISA.

Quick Overview for PAK1/2/3 antibody (pThr423) (ABIN481976)

Target: PAK1/2/3 (P21-Activated Kinases 1/2/3 (PAK1/2/3))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PAK1/2/3 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Product Details anti-PAK1/2/3 Antibody

Binding Specificity: AA 391-440, pThr423

Specificity:

PAK1/2/3 (Phospho-Thr423/402/421) Antibody detects endogenous levels of PAK1/2/3 only when phosphorylated at Thr423/402/421.

PhosphorylationH:T423/402/421 M:T423/402/421 R:T422/402/421

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human PAK1/2/3 around the phosphorylation site of Thr423/402/421.

Isotype: IgG

Application Details

Application Notes: IHC: 1:50~1:100 ELISA: 1:5000

Comment:

Unigene-Number: Hs.435714, Hs.518530, Hs.656789 (NCBI Gene Symbol: PAK1)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for PAK1/2/3

Target: PAK1/2/3 (P21-Activated Kinases 1/2/3 (PAK1/2/3))

Alternative Name: PAK1/2/3

Background:

Synonyms: Gamma-PAK, P21-activated kinase 2, PAK 2, PAK-2, PAK65, PAKI, S6/H4 kinase, kinase PAK2, p21-activated kinase 2, p21-activated protein kinase IBeta-PAK, CDC42/RAC effector kinase PAK-B, OPHN3, Oligophrenin-3, P65-PAK, PAK 3, PAK-3, PAKB, STK4, Serine/thre

NCBI Gene Symbol: PAK1

Molecular Weight: 60 kDa

Gene ID: 5058, 5062, 5063

OMIM: 602590

UniProt: Q13153, Q13177, O75914