PDGFRB antibody (pTyr1021)

Catalog No. ABIN482234

The Rabbit Polyclonal anti-PDGFRB antibody is suitable to detect PDGFRB in samples from Human, Mouse and Rat. It has been validated for ELISA and IHC.

Quick Overview for PDGFRB antibody (pTyr1021) (ABIN482234)

Target: PDGFRB (Platelet Derived Growth Factor Receptor beta (PDGFRB))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDGFRB antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-PDGFRB Antibody

Binding Specificity: AA 991-1040, pTyr1021

Specificity:

PDGFR beta (Phospho-Tyr1021) Antibody detects endogenous levels of PDGFR beta only when phosphorylated at Tyr1021.

PhosphorylationH:Y1021 M:Y1020 R:Y1020

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human PDGFR beta around the phosphorylation site of Tyr1021.

Isotype: IgG

Application Details

Application Notes: IHC: 1:50~1:100 ELISA: 1:1000

Comment:

Unigene-Number: Hs.509067 (NCBI Gene Symbol: PDGFRB)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for PDGFRB

Target: PDGFRB (Platelet Derived Growth Factor Receptor beta (PDGFRB))

Alternative Name: PDGFR beta

Background:

Synonyms: CD140b, kinase PDGFR-beta, PDGF-R-beta, PDGFR, PDGFR-beta, PGFRB, platelet-derived growth factor receptor, beta polypeptide

NCBI Gene Symbol: PDGFRB

Molecular Weight: 123 kDa

Gene ID: 5159

OMIM: 131440

UniProt: P09619

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Inositol Metabolic Process, Glycosaminoglycan Metabolic Process, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling