Recombinant PDGFRB antibody

Catalog No. ABIN7795629

The Rabbit Monoclonal anti-PDGFRB antibody is suitable to detect PDGFRB in samples from Mouse. It has been validated for WB, FACS, ICC and IP.

Quick Overview for Recombinant PDGFRB antibody (ABIN7795629)

Target: PDGFRB (Platelet Derived Growth Factor Receptor beta (PDGFRB))

Antibody Type: Recombinant Antibody

Reactivity: Mouse

Host: Rabbit

Clonality: Monoclonal

Conjugate: This PDGFRB antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunoprecipitation (IP)

Clone: BLR242L

Product Details anti-PDGFRB Antibody

Purpose: Rabbit anti-PDGFR beta Recombinant Monoclonal Antibody [BLR242L]

Purification: Purified

Immunogen: Residues 32-530 (ECD)

Isotype: IgG

Application Details

Application Notes: Flow-Cyt,Fixed in 4 % formaldehyde and permeabilized with 90 % methanol. 0.05 μL per 1 x 10^6 cells.,ICC,1100 to 1500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.,IP,6 μL/mg lysate ,WB,11000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1000 μg/mL

Buffer: Borate Buffered Saline (BBS) pH 8.2 with 0.09 % Sodium Azide, BSA-Free

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: 2 - 8 °C

Expiry Date: 12 months

Target Details for PDGFRB

Target: PDGFRB (Platelet Derived Growth Factor Receptor beta (PDGFRB))

Alternative Name: PDGFR beta

Background: Platelet derived growth factor receptor beta is a cell surface tyrosine kinase receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB. These growth factors are members of the platelet-derived growth factor family and are mitogens for cells of mesenchymal origin. PDGFR beta is essential for normal development of the cardiovascular system and aids in rearrangement of the actin cytoskeleton. [taken from NCBI Entrez Gene (Gene ID: 5159)].

Gene ID: 18596

UniProt: P05622

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Inositol Metabolic Process, Glycosaminoglycan Metabolic Process, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling