MCL-1 antibody (pSer159)

Catalog No. ABIN482299

This Rabbit Polyclonal antibody specifically detects MCL-1 in ELISA and IF. It exhibits reactivity toward Human and Mouse.

Quick Overview for MCL-1 antibody (pSer159) (ABIN482299)

Target: MCL-1 (MCL1) (Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MCL-1 antibody is un-conjugated

Application: ELISA, Immunofluorescence (IF)

Product Details anti-MCL-1 Antibody

Binding Specificity: AA 125-174, pSer159

Specificity:

MCL1 (Phospho-Ser159) Antibody detects endogenous levels of MCL1 only when phosphorylated at Ser159.

PhosphorylationH:S159 M:S140

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human MCL1 around the phosphorylation site of Ser159.

Isotype: IgG

Application Details

Application Notes: IF: 1:100~1:500 ELISA: 1:1000

Comment:

Unigene-Number: Hs.713518 (NCBI Gene Symbol: MCL1)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for MCL-1

Target: MCL-1 (MCL1) (Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1))

Alternative Name: MCL1

Background:

Synonyms: Bcl-2-related protein EAT/mcl1, EAT/MCL-1, induced myeloid leukemia cell differentiation protein Mcl-1, mcl1/EAT, myeloid cell leukemia sequence 1

NCBI Gene Symbol: MCL1

Molecular Weight: 37 kDa

Gene ID: 4170

OMIM: 159552

UniProt: Q07820

Pathways: MAPK Signaling