MCL-1 antibody (AA 191-226)

Catalog No. ABIN3031299

The Rabbit Polyclonal anti-MCL-1 antibody (ABIN3031299) specifically detects MCL-1 in WB, ELISA, IHC and FACS. The antibody is reactive with Human and Mouse samples.

Quick Overview for MCL-1 antibody (AA 191-226) (ABIN3031299)

Target: MCL-1 (MCL1) (Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MCL-1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Product Details anti-MCL-1 Antibody

Binding Specificity: AA 191-226

Purpose: MCL1 Antibody

Purification: Purified

Immunogen: A portion of amino acids 191-226 from the human protein was used as the immunogen for this MCL1 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the MCL1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the MCL1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for MCL-1

Target: MCL-1 (MCL1) (Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1))

Alternative Name: MCL1

Background: The Mcl-1 protein belongs to the Bcl-2 family. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified. The longer gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene product (isoform 2) promotes apoptosis and is death-inducing.

UniProt: Q07820

Pathways: MAPK Signaling