NR4A1 antibody (pSer351)

Catalog No. ABIN482333

The Rabbit Polyclonal anti-NR4A1 antibody is suitable to detect NR4A1 in samples from Human, Rat and Mouse. It has been validated for ELISA and IHC.

Quick Overview for NR4A1 antibody (pSer351) (ABIN482333)

Target: NR4A1 (Nuclear Receptor Subfamily 4, Group A, Member 1 (NR4A1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NR4A1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-NR4A1 Antibody

Binding Specificity: AA 317-366, pSer351

Specificity:

Nuclear Receptor NR4A1 (Phospho-Ser351) Antibody detects endogenous levels of Nuclear Receptor NR4A1 only when phosphorylated at Ser351.

PhosphorylationH:S351 M:S354 R:S350

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human Nuclear Receptor NR4A1 around the phosphorylation site of Ser351.

Isotype: IgG

Application Details

Application Notes: IHC: 1:50~1:100 ELISA: 1:40000

Comment:

Unigene-Number: Hs.524430 (NCBI Gene Symbol: NR4A1)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for NR4A1

Target: NR4A1 (Nuclear Receptor Subfamily 4, Group A, Member 1 (NR4A1))

Background:

Synonyms: Early response protein NAK1, GFRP, GFRP1, HMR, N10, N10 nuclear protein, NAK1, NGFI-B, NGFIB, NR4A1, Nuclear hormone receptor NUR/77, Orphan nuclear receptor HMR, TR3 orphan receptor

NCBI Gene Symbol: NR4A1

Molecular Weight: 64 kDa

Gene ID: 3164

OMIM: 139139

UniProt: P22736

Pathways: Fc-epsilon Receptor Signaling Pathway, Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Steroid Hormone Mediated Signaling Pathway