APLP2 antibody (pTyr755)

Catalog No. ABIN482735

The Rabbit Polyclonal anti-APLP2 antibody is suitable to detect APLP2 in samples from Human, Mouse and Rat. It has been validated for IHC and ELISA.

Quick Overview for APLP2 antibody (pTyr755) (ABIN482735)

Target: APLP2 (Amyloid beta (A4) Precursor-Like Protein 2 (APLP2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This APLP2 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Product Details anti-APLP2 Antibody

Binding Specificity: AA 714-763, pTyr755

Specificity:

APLP2 (Phospho-Tyr755) Antibody detects endogenous levels of APLP2 only when phosphorylated at Tyr755.

PhosphorylationH:Y755 M:Y687 R:Y757

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human APLP2 around the phosphorylation site of Tyr755.

Isotype: IgG

Application Details

Application Notes: IHC: 1:50~1:100 ELISA: 1:20000

Comment:

Unigene-Number: Hs.709184 (NCBI Gene Symbol: APLP2)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for APLP2

Target: APLP2 (Amyloid beta (A4) Precursor-Like Protein 2 (APLP2))

Alternative Name: APLP2

Background:

Synonyms: Amyloid protein homolog, Amyloid-like protein 2 precursor, APLP2, APP2, APPH, APPL2, CDEBP, CDEI-box binding protein

NCBI Gene Symbol: APLP2

Molecular Weight: 86 kDa

Gene ID: 334

OMIM: 104776

UniProt: Q06481

Pathways: EGFR Signaling Pathway, Transition Metal Ion Homeostasis, Feeding Behaviour