VHL antibody (AA 34-83)

Catalog No. ABIN483819

The Rabbit Polyclonal anti-VHL antibody (ABIN483819) specifically detects VHL in IHC and ELISA. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for VHL antibody (AA 34-83) (ABIN483819)

Target: VHL (Von Hippel-Lindau Tumor Suppressor, E3 Ubiquitin Protein Ligase (VHL))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VHL antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Product Details anti-VHL Antibody

Binding Specificity: AA 34-83

Specificity:

VHL Antibody detects endogenous levels of total VHL protein.

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human VHL.

Isotype: IgG

Application Details

Application Notes: IHC: 1:50~1:100 ELISA: 1:40000

Comment:

Unigene-Number: Hs.517792 (NCBI Gene Symbol: VHL)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for VHL

Target: VHL (Von Hippel-Lindau Tumor Suppressor, E3 Ubiquitin Protein Ligase (VHL))

Alternative Name: VHL

Background:

Synonyms: G7 protein, pVHL, Von Hippel-Lindau disease tumor suppressor, von Hippel-Lindau syndrome gene

NCBI Gene Symbol: VHL

Molecular Weight: 24 kDa

Gene ID: 7428

OMIM: 144700

UniProt: P40337

Pathways: Tube Formation, Signaling Events mediated by VEGFR1 and VEGFR2, Ubiquitin Proteasome Pathway