GRP78 antibody (AA 605-654)

Catalog No. ABIN483915

The Rabbit Polyclonal anti-GRP78 antibody (ABIN483915) specifically detects GRP78 in WB, IHC, ELISA and IF. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for GRP78 antibody (AA 605-654) (ABIN483915)

Target: GRP78 (HSPA5) (Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GRP78 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-GRP78 Antibody

Binding Specificity: AA 605-654

Specificity:

GRP78 Antibody detects endogenous levels of total GRP78 protein.

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human GRP78.

Isotype: IgG

Application Details

Application Notes: WB: 1:500~1:1000 IHC: 1:50~1:100 IF: 1:100~1:500 ELISA: 1:5000

Comment:

Unigene-Number: Hs.724412 (NCBI Gene Symbol: HSPA5)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for GRP78

Target: GRP78 (HSPA5) (Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5))

Alternative Name: GRP78

Background:

Synonyms: 78 kDa glucose-regulated protein, GRP-78, Heat shock 70 kDa protein 5, Immunoglobulin heavy chain-binding protein, BiP, Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78 , HSPA5 , GRP78

NCBI Gene Symbol: HSPA5

Molecular Weight: 72 kDa

Gene ID: 3309

OMIM: 138120

UniProt: P11021

Pathways: Thyroid Hormone Synthesis, ER-Nucleus Signaling