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Antibodies
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anti-Guanine Nucleotide Binding Protein (G Protein), alpha 15 (Gq Class) (GNA15) a...
Guanine Nucleotide Binding Protein (G Protein), alpha 15 (Gq Class) (GNA15) antibody
| Antigen |
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| Synonyms |
GNA16, G[a]15, Galpha15 |
| Clonality |
Polyclonal |
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Host
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Reactivity
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Application
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| Catalog no. |
ABIN488048 |
| Quantity |
0.1 mg (0.5 mg/ml) |
| Price |
300.00 $ Plus shipping costs $35.00
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| Shipping to |
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| Availability |
Ships within 7 to 10 Business Days |
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Characteristics
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Synonyms: G alpha-15, GNA15, GNA16, Guanine nucleotide-binding protein subunit alpha-15
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Alternative name
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G protein alpha 15
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Gene ID
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2769
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Swiss-Prot
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P30679
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Immunogen
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Synthetic peptide surrounding amino acid 356 of Human G Protein Alpha 15
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Cross-Reactivity
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Human, Mouse (Murine), Rabbit, Rat (Rattus)
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Description
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G Protein alpha 16 (GA16) is the only heterotrimeric G protein with a restricted expressionpattern in hematopoietic cells. Differentiation of promyelocytic cells leads to decreasedexpression of GA16. The G protein is known to couple a large number of G protein-coupledreceptors to PLC-beta and can lead to production of the secondary messengersdiacylglycerol and inositol phosphates. Targeted deletion of GA15, a mouse orthologue ofhuman GA16, causes reduced C5α receptor signaling. GA16 serves as a marker, in additionto CD34, for hematopoietic progenitor cells.
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Specificity
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The antibody detects GA15 in samples from Human, Mouse, Rat, and Rabbit origins. It also detects GA16 from samples of Human origin. Species: Human, Mouse, Rat and Rabbit. Others not tested.
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Application Notes
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Western blotting (0.5-4 µg/ml). From Researcher's feedback, the antibody can be used in Immunohistochemistry (5-20µg/ml). Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
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Concentration
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0.5 mg/ml
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Purification
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Aff - Purified
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Buffer
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PBS (pH 7.2) containing 30% Glycerol, 0.5% BSA and 0.01% Thimerosal aspreservative.
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Storage
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Store the antibody undiluted at -20°C or for long term storage (in aliquots) at -70°C. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
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Restrictions
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For Research Use only
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Alternatives for antigen "Guanine Nucleotide Binding Protein (G Protein), alpha 15 (Gq Class) (GNA15)", type "Antibodies"
Alternatives 
