SYN2 antibody (AA 497-582)

Catalog No. ABIN4886735

Product Details anti-SYN2 Antibody

Target: SYN2 (Synapsin II (SYN2))

Binding Specificity: AA 497-582

Reactivity: Mouse, Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SYN2 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit IgG polyclonal antibody for Synapsin-2(SYN2) detection. Tested with WB in Human,Mouse,Rat.

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for Synapsin-2(SYN2) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: synapsin II
Protein Name: Synapsin-2

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human Synapsin II recombinant protein (Position: A497-D582). Human Synapsin II shares 93.1% and 89.7% amino acid (aa) sequence identity with mouse and rat Synapsin II, respectively.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Target Details for SYN2

Target: SYN2 (Synapsin II (SYN2))

Alternative Name: SYN2 (SYN2 Products)

Synonyms: synII antibody, synIIa antibody, synIIb antibody, syn1 antibody, syn2 antibody, zgc:92311 antibody, MGC115109 antibody, SYN2 antibody, SYNII antibody, SYNIIa antibody, SYNIIb antibody, 2900074L19Rik antibody, AI836018 antibody, AI841723 antibody, synapsin II L homeolog antibody, synapsin II antibody, synapsin IIa antibody, synapsin II S homeolog antibody, synapsin-2 antibody, syn2.L antibody, SYN2 antibody, syn2a antibody, syn2.S antibody, EDI_190690 antibody, Syn2 antibody

Background: Synapsin II is the collective name for synapsin IIa and synapsin IIb, two nearly identical phosphoproteins in the synapsin family that in humans are encoded by the SYN2 gene. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. This member of the synapsin family encodes a neuron-specific phosphoprotein that selectively binds to small synaptic vesicles in the presynaptic nerve terminal. Polymorphisms in this gene are associated with abnormal presynaptic function and related neuronal disorders, including autism, epilepsy, bipolar disorder and schizophrenia. Alternative splicing of this gene results in multiple transcript variants. The tissue inhibitor of metalloproteinase 4 gene is located within an intron of this gene and is transcribed in the opposite direction.

Synonyms: SYN 2 | SYN II | SYN IIa | SYN IIb | SYN2 | Synapsin 2 | Synapsin2 | SynapsinII | SYNII | SYNIIa | SYNIIb | Q92777

Gene ID: 6854

UniProt: Q92777