LASS1 antibody (AA 318-329)

Catalog No. ABIN490420

Product Details anti-LASS1 Antibody

Target: LASS1 (CERS1) (Ceramide Synthase 1 (CERS1))

Binding Specificity: AA 318-329

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This LASS1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: Human LASS1. This antibody is expected to recognize both reported isoforms (NP_067090.1and NP_937850.1).

Predicted Reactivity: Percent identity by BLAST analysis: Human, Gibbon (100%) Monkey, Marmoset (92%) Mouse, Hamster, Bovine, Pig (83%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide C-KDLREYDTAEAQ from an internal region of human LASS1 (NP_067090.1, NP_937850.1). Percent identity by BLAST analysis: Human, Gibbon (100%), Monkey, Marmoset (92%), Mouse, Hamster, Bovine, Pig (83%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: Peptide-ELISA (1:64000), WB (1 - 3 μg/mL)

Usage: Peptide ELISA: antibody detection limit dilution 1:64000. Western blot: Approx. 37 kDa band observed in Human Brain (Cerebellum, Cerebral Cortex and Frontal Cortex) lysates (calculated MW of 38.0 kDa according to NP_937850.1). Recommended concentration: 1-3 μg/mL. An additional band of unknown identity was also consistently observed at 85 kDa. This band was successfully blocked by incubation with the immunising peptide.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for LASS1

Target: LASS1 (CERS1) (Ceramide Synthase 1 (CERS1))

Alternative Name: LASS1 (CERS1 Products)

Synonyms: LAG1 antibody, LASS1 antibody, UOG1 antibody, Lass1 antibody, Uog-1 antibody, to antibody, LAG1 HOMOLOG 1 antibody, LONGEVITY ASSURANCE GENE 1 antibody, ceramide synthase 1 antibody, TRAM, LAG1 and CLN8 (TLC) lipid-sensing domain containing protein antibody, CERS1 antibody, Cers1 antibody, LAG1 antibody

Background: Name/Gene ID: CERS1
Family: TGF beta

Synonyms: CERS1, LAG1, Protein UOG-1, UOG1, Upstream of GDF1, Ceramide synthase 1, LASS1

Gene ID: 10715

NCBI Accession: NP_067090, NP_937850

UniProt: P27544