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CD4 Molecule (CD4) antibody

Antigen

CD4 Molecule (CD4)
Synonyms CD4, MGC165891, cd4, CD4mut, L3T4, Ly-4, p55, W3/25
Clonality Polyclonal
Host
Alternatives

Mouse
Reactivity
Alternatives

Human
Application
Alternatives Enzyme Immunoassay (EIA), Western Blotting (WB)
Catalog no. ABIN492544
Quantity 0.1 mg  (Variants)
Price 320.00 $   Plus shipping costs $35.00
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Availability Ships within 7 to 10 Business Days

Additional Information
Application Details Alternatives Secondary Antibodies Variants back to top

Characteristics Synonyms: T4/Leu-3, T-cell surface glycoprotein CD4, T-cell surface antigen T4/Leu-3
Alternative name CD4
Gene ID 920
Swiss-Prot P01730
Immunogen A 193 amino acid recombinant protein from near the amino terminus of Human CD4(GenBank accession No. NP_000607)
Cross-Reactivity Human, Mouse (Murine), Rat (Rattus)
Isotype IgG  (Matching secondary antibodies)
Description CD4 is a member of the immunoglobulin superfamily and is implicated as associativerecognition element in MHC (Major Histocompatibility Complex) class II-restricted immuneresponse. On T-lymphocytes, it defines the helper/inducer subset. The mature 55 kd CD4protein consists of a 372 amino acid extracellular segment composed of four tandemimmunoglobulin-like VJ regions. The CD4 molecule is a major receptor for humanimmunodeficiency virus (HIV), binding directly to the envelope glycoprotein gp120 on HIV,with the co-receptors being CCR5 or CXCR4. It has been shown that the V-like domains arecritical for binding with HIV envelope gp120.
Specificity Recognizes CD4Species: Human, Mouse and Rat. Others not tested. Add. Information: Related Products: ABIN492543: CD4 Antibody (9H5A8)ABIN499906: gp120 AntibodyABIN499696: CXCR4 Antibody (N-term)

Application Details
Alternatives Secondary Antibodies Variants back to top

Application Notes ELISA. Western Blot: CD4 antibody can be used for detection of CD4 at 0.5-1 µg/ml. Positive Control: Rat Lung Tissue Lysate. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Purification Aff - Purified
Buffer PBS containing 0.02% Sodium Azide as preservative.
Storage Store the antibody undiluted at 2-8°C. Shelf life: one year from despatch.
Research Area Immunology, Adaptive Immunity, Hematopoietic Progenitors, CD Antigens, Surface Receptors of Immune Cells
Restrictions For Research Use only

Alternatives
Application Details Secondary Antibodies Variants back to top

Alternatives for antigen "CD4 Molecule (CD4)", type "Antibodies"
Hosts Mouse (444), Rat (208), Rabbit (68)
Reactivities Human (320), Mouse (Murine) (238), Rat (Rattus) (105), Dog (Canine) (44), Chicken (34), Cow (Bovine) (34), Sheep (Ovine) (24), Pig (Porcine) (22), Cat (Feline) (20), Rabbit (20), Bird (Avian) (8), Guinea Pig (8), Horse (Equine) (4), Duck (3), Monkey (3)
Applications Flow Cytometry (FACS) (602), Immunohistochemistry (Frozen Sections) (IHC (fro)) (149), Immunoprecipitation (IP) (93), Western Blotting (WB) (82), Immunofluorescence (IF) (53), ELISA (50), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (49), Functional Studies (Func) (35), Immunohistochemistry (IHC) (29), Immunocytochemistry (ICC) (16), Blocking Antibody (Inhibition) (11), Cytotoxicity Test (CyTox) (11), Enzyme Immunoassay (EIA) (8), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (4), Immunoelectron Microscopy (IEM) (2), Blocking Antibody (Inhibition) (1), ELISA (Detection) (1), Immunohistochemistry (Fixed) (IHC (fx)) (1), Neutralization (Neut) (1)
Conjugates FITC (116), PE (77), Biotin (71), APC (40), RPE (22), Cy5 (9), Cy5,PE (9), Cy5.5 (6), Cy7,PE (6), Alexa Fluor 488 (5), PE,Cy7 (5), HRP (4), PE,Cy5.5 (4), Pacific Blue (4), APC,Cy7 (3), PE,Cy5 (3), PerCP (3), SPRD (3), Alexa Flour 488 (2), Alexa Fluor 350 (2), Alexa Fluor 555 (2), Alexa Fluor 647 (2), Alexa Fluor 700 (2), Cy3 (2), Cy7 (2), Gold (2), PE,Cy3 (2), RBITC (2), DY647 (1), Dyomics 647 (1), PE,DY590 (1), PE,DY647 (1), PE,Texas Red (TR) (1), PE-Dyomics 590 (1), PE-Dyomics 647 (1), PerCP,Cy5.5 (1), RPE,Cy5 (1), RPE,Cy7 (1)
Epitopes domain 1 (10), domain 2 (5), non-polymorphic (5)