CTNNA1 antibody (Ser641)

Catalog No. ABIN540503

Product Details anti-CTNNA1 Antibody

Target: CTNNA1 (Catenin (Cadherin-Associated Protein), alpha 1, 102kDa (CTNNA1))

Binding Specificity: Ser641

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CTNNA1 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit polyclonal antibody raised against synthetic peptide of CTNNA1.

Sequence: DDSDF

Specificity: Alpha-catenin (Ab-641) antibody detects endogenous levels of total alpha-catenin protein.

Cross-Reactivity: Human, Mouse

Characteristics: Antibody Reactive Against Synthetic Peptide.

Immunogen: A synthetic peptide (conjugated with KLH) corresponding to residues surrounding S641 of human CTNNA1.

Application Details

Application Notes: Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: In PBS (without Mg²⁺ and Ca²⁺), 150 mM NaCl, pH 7.4 (50 % glycerol, 0.02 % sodium azide)

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C.
Aliquot to avoid repeated freezing and thawing.

References for anti-CTNNA1 antibody (ABIN540503)

Yamada, Pokutta, Drees, Weis, Nelson: "Deconstructing the cadherin-catenin-actin complex." in: Cell, Vol. 123, Issue 5, pp. 889-901, (2005) (PubMed).

Drees, Pokutta, Yamada, Nelson, Weis: "Alpha-catenin is a molecular switch that binds E-cadherin-beta-catenin and regulates actin-filament assembly." in: Cell, Vol. 123, Issue 5, pp. 903-15, (2005) (PubMed).

Hwang, Yu, Ryu, Jeon, Yoo, Eom, Chun: "Regulation of beta-catenin signaling and maintenance of chondrocyte differentiation by ubiquitin-independent proteasomal degradation of alpha-catenin." in: The Journal of biological chemistry, Vol. 280, Issue 13, pp. 12758-65, (2005) (PubMed).

Target Details for CTNNA1

Target: CTNNA1 (Catenin (Cadherin-Associated Protein), alpha 1, 102kDa (CTNNA1))

Alternative Name: Catenin alpha-1 / CTNNA1 (CTNNA1 Products)

Synonyms: CAP102 antibody, 2010010M04Rik antibody, AA517462 antibody, AI988031 antibody, Catna1 antibody, CG17947 antibody, CT39986 antibody, Dalpha-Cat antibody, Dalpha-cat antibody, DalphaC antibody, Dalphacat antibody, Dmcatp antibody, Dmel\\CG17947 antibody, a-Cat antibody, a-cat antibody, alpha-CAT antibody, alpha-cat antibody, alpha-catenin antibody, alpha-ctn antibody, alphaCAT antibody, alphaCat antibody, alphacat antibody, Alpha-Cat antibody, dgri_GLEANR_3829 antibody, DgriGH19548 antibody, GH19548 antibody, ctnna antibody, cap102 antibody, catna1 antibody, ctnna1 antibody, catenin alpha 1 antibody, catenin (cadherin associated protein), alpha 1 antibody, alpha Catenin antibody, catenin alpha-1 antibody, catenin (cadherin-associated protein), alpha 1 antibody, catenin alpha 1 S homeolog antibody, CTNNA1 antibody, Ctnna1 antibody, alpha-Cat antibody, Dgri\alpha-Cat antibody, Tsp_10127 antibody, ctnna1 antibody, ctnna1.S antibody

Gene ID: 1495

Pathways: Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Maintenance of Protein Location