MYST2 antibody

Catalog No. ABIN498300

The Rabbit Polyclonal anti-MYST2 antibody (ABIN498300) specifically detects MYST2 in WB and IF. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for MYST2 antibody (ABIN498300)

Target: MYST2 (MYST Histone Acetyltransferase 2 (MYST2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MYST2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-MYST2 Antibody

Specificity: This antibody detects endogenous levels of HBO1 protein. (region surrounding Ser167)

Cross-Reactivity (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Purification: Affinity-chromatography using epitope-specific immunogen

Application Details

Application Notes: Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for MYST2

Target: MYST2 (MYST Histone Acetyltransferase 2 (MYST2))

Alternative Name: MYST2

Background: KAT7 / Hbo1 is a member of the MYST histone acetyltransferae family which acetylates both histone H3 and H4 and is involved in the regulation of replication. The initiation of DNA replication is tightly regulated in eukaryotic cells to ensure that the genome is precisely duplicated once per cell cycle. This is accomplished by controlling the pre-replicative complex. KAT7 acts as a positive regulatory factor for pre-RC assembly and thus controls DNA replication.Synonyms: HBO1, HBOa, Histone acetyltransferase MYST2, Histone acetyltransferase binding to ORC1, MOZ, SAS2, TIP60 protein 2, YBF2/SAS3

Molecular Weight: approx. 75 kDa

Gene ID: 11143

NCBI Accession: NP_008998

UniProt: O95251