MYST2 antibody (AA 1-214)

Catalog No. ABIN7155278

Product Details anti-MYST2 Antibody

Target: MYST2 (MYST Histone Acetyltransferase 2 (MYST2))

Binding Specificity: AA 1-214

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MYST2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human, Rat

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Histone acetyltransferase KAT7 protein (1-214AA)

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for MYST2

Target: MYST2 (MYST Histone Acetyltransferase 2 (MYST2))

Alternative Name: KAT7 (MYST2 Products)

Synonyms: Myst2 antibody, HBO1 antibody, HBOA antibody, MYST2 antibody, ZC2HC7 antibody, Hbo1 antibody, Hboa antibody, lysine acetyltransferase 7 antibody, K(lysine) acetyltransferase 7 antibody, MYST histone acetyltransferase 2 antibody, Kat7 antibody, KAT7 antibody, myst2 antibody

Background:

Background: Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Involved in H3K14 (histone H3 lysine 14) acetylation and cell proliferation (By similarity). Through chromatin acetylation it may regulate DNA replication and act as a coactivator of TP53-dependent transcription. Acts as a coactivator of the licensing factor CDT1 (PubMed:18832067). Specifically represses AR-mediated transcription.

Aliases: Hbo 1 antibody, HBO1 antibody, HBOa antibody, Histone acetyltransferase binding to hORC1 antibody, Histone acetyltransferase binding to ORC1 antibody, Histone acetyltransferase KAT7 antibody, Histone acetyltransferase MYST2 antibody, K(lysine) acetyltransferase 7 antibody, KAT 7 antibody, KAT7 antibody, Lysine acetyltransferase 7 antibody, MOZ antibody, MOZ YBF2/SAS3 SAS2 and TIP60 protein antibody, MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2 antibody, MYST 2 antibody, MYST histone acetyltransferase 2 antibody, MYST protein 2 antibody, MYST-2 antibody, MYST2 antibody, MYST2_HUMAN antibody, SAS 2 antibody, SAS2 and TIP60 protein 2 antibody, TIP60 protein 2 antibody, YBF2/SAS3 antibody, ZC2HC7 antibody

UniProt: O95251