MYST2 antibody (Internal Region)

Catalog No. ABIN2855265

Product Details anti-MYST2 Antibody

Target: MYST2 (MYST Histone Acetyltransferase 2 (MYST2))

Binding Specificity: Internal Region

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MYST2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Chicken, Pig (Porcine), Rat (Rattus), Xenopus laevis, Zebrafish (Danio rerio), Cow (Bovine)

Cross-Reactivity (Details): Chicken (98 %), Pig (99 %), Rat (100 %), Xenopus laevis (94 %), Zebrafish (84 %), Bovine (99 %)

Characteristics: Rabbit Polyclonal antibody to MYST2 (MYST histone acetyltransferase 2)
MYST2 antibody [N2C1], Internal

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human MYST2. The exact sequence is proprietary.

Isotype: IgG

Application Details

Application Notes: Suggested dilution Reference IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceIHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*

Comment:

Positive Control: NT2D1 , IMR32 , MCF-7 , mouse brain

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.33 mg/mL

Buffer: 1XPBS, 1 % BSA, 20 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Target Details for MYST2

Target: MYST2 (MYST Histone Acetyltransferase 2 (MYST2))

Alternative Name: MYST2 (MYST2 Products)

Synonyms: Myst2 antibody, HBO1 antibody, HBOA antibody, MYST2 antibody, ZC2HC7 antibody, Hbo1 antibody, Hboa antibody, lysine acetyltransferase 7 antibody, K(lysine) acetyltransferase 7 antibody, MYST histone acetyltransferase 2 antibody, Kat7 antibody, KAT7 antibody, myst2 antibody

Background: Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Through chromatin acetylation it may regulate DNA replication and act as a coactivator of TP53-dependent transcription. Specifically represses AR-mediated transcription.

Cellular Localization: Nucleus , nucleoplasm

Molecular Weight: 71 kDa

Gene ID: 11143