Cathepsin D (CTSD) antibody
| Antigen |
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| Synonyms |
CPSD, CLN10, MGC2311, CD, CatD, catD, fb93e11, fj17b09, wu:fb93e11, wu:fj17b09, CTSD, LOC398557, Cathd, LOC100136761, DKFZp469J0315 |
| Clonality |
Polyclonal |
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Host
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Reactivity
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Application
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 Alternatives Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
Western Blotting (WB) (37), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (23), ELISA (16), Enzyme Immunoassay (EIA) (10), Immunohistochemistry (IHC) (10), Immunohistochemistry (Frozen Sections) (IHC (fro)) (6), Immunoprecipitation (IP) (5), ELISA (Detection) (4), Immunocytochemistry (ICC) (3), Flow Cytometry (FACS) (2), Immunoelectrophoresis (IEP) (1), To be determined by user (TBD) (1)
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| Catalog no. |
ABIN498665 |
| Quantity |
100 µg (1,0 mg/ml) (Variants) |
| Price |
340.00 $ Plus shipping costs $35.00
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| Shipping to |
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| Availability |
Ships within 7 to 10 Business Days |
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Characteristics
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Synonyms: CTSD, CPSD
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Alternative name
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Cathepsin D
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Gene ID
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1509
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Swiss-Prot
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P07339
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Cross-Reactivity
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Human
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Description
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The cathepsin family of proteolytic enzymes contains several diverse classes of proteases. The cysteine protease class comprises cathepsins B, L, H, K, S, and O. The aspartylprotease class is composed of cathepsins D and E. Cathepsin G is in the serine proteaseclass. Most cathepsins are lysosomal and each is involved in cellular metabolism,participating in various events such as peptide biosynthesis and protein degradation. Cathepsins may also cleave some protein precursors, thereby releasing regulatorypeptides. The promoter region of the cathepsin D gene contains five Sp1 binding sites andfour AP-2 binding sites.
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Specificity
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Cathepsin D pAb detects endogenous levels of Cathepsin D protein. Species: Human. Others not tested.
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Application Notes
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Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
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Concentration
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1,0 mg/ml
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Purification
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Aff - Purified
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Buffer
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Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2.
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Storage
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Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
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Research Area
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Proteolysis / Ubiquitin, Extracellular Matrix, Proteases, Signaling
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Restrictions
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For Research Use only
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Alternatives for antigen "Cathepsin D (CTSD)", type "Antibodies"
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Hosts
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Rabbit (32), Mouse (19), Goat (1)
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Reactivities
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Human (49), Mouse (Murine) (6), Rat (Rattus) (5)
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Applications
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Western Blotting (WB) (37), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (23), ELISA (16), Enzyme Immunoassay (EIA) (10), Immunohistochemistry (IHC) (10), Immunohistochemistry (Frozen Sections) (IHC (fro)) (6), Immunoprecipitation (IP) (5), ELISA (Detection) (4), Immunocytochemistry (ICC) (3), Flow Cytometry (FACS) (2), Immunoelectrophoresis (IEP) (1), To be determined by user (TBD) (1)
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Epitopes
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Center (1)
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