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interleukin 23, alpha subunit p19 (IL23A) (N-Term) antibody

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Antigen
Synonyms IL-23, IL-23A, IL23P19, P19, SGRF, p19, IL23, il23p19, FIL1, FIL1(ZETA), FIL1Z, IL-1F7, IL-1H, IL-1H4, IL-1RP1, IL-37, IL1F7, IL1H4, IL1RP1
Epitope
N-Term
(13), (10), (9), (5), (1), (1), (1), (1)
Reactivity
Human, Mouse (Murine)
(80), (35), (13)
Host
Rabbit
(55), (21), (15), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(65), (25), (15), (10), (9), (7), (6), (5), (5), (4), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Pubmed 1 reference available
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Quantity 0.1 mg
Shipping to United States ( )
Availability Will be delivered in 6 to 8 Business Days
Immunogen IL-23 antibody was raised against a 16 amino acid peptide from near the amino terminus of human IL-23.
Isotype IgG
Specificity This antibody reacts to Il-23.
Purification Affinity chromatography purified via peptide column
Alternative Name Interleukin-23 alpha / IL23A (IL23A Antibody Abstract)
Background Like interleukin-27 (IL-27), IL-23 is a recently discovered member of the IL-6/IL-12 family of proinflammatory and immunoregulatory cytokines. It exists as a heterodimer composed of the IL-12p40 subunit and a novel p19 subunit. IL-23 is secreted by activated dendritic cells, macrophages, and monocytes (3,4). Its biological activities include enhancing the proliferation of memory T cells and the production of IFN-gamma, IL-12, and TNF-alpha from activated T cells, and can stimulate macrophages to produce TNF-alpha and nitric oxide. It has also been shown to possess potent anti-tumor and anti-metastatic activity in mouse models of cancer, suggesting a potential role for IL-23 in therapeutic treatment of cancer.Synonyms: IL-23 subunit alpha, IL-23p19, Interleukin-23 subunit p19, SGRF
Gene ID 51561
UniProt Q9NPF7
Application Notes ELISA. Western Blot: 1 - 2 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Buffer PBS containing 0.02 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-interleukin 23, alpha subunit p19 (IL23A) (N-Term) antibody (ABIN499998) Immunohistochemistry of IL-23 in mouse pancreas tissue with IL-23 antibody at 2 μg/ml.
Western Blotting (WB) image for anti-interleukin 23, alpha subunit p19 (IL23A) (N-Term) antibody (ABIN499998) Western blot analysis of IL-23 in mouse pancreas tissue lysate with AP30419PU-N IL-23...
Background publications Hunter: "New IL-12-family members: IL-23 and IL-27, cytokines with divergent functions." in: Nature reviews. Immunology, Vol. 5, Issue 7, pp. 521-31, 2005 (PubMed).

Catalog No. ABIN499998
$401.50
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