interleukin 23, alpha subunit p19 (IL23A) (N-Term) antibody

Details for Product No. ABIN499998
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Synonyms IL-23, IL-23A, IL23P19, P19, SGRF, p19, IL23, il23p19, FIL1, FIL1(ZETA), FIL1Z, IL-1F7, IL-1H, IL-1H4, IL-1RP1, IL-37, IL1F7, IL1H4, IL1RP1
(26), (21), (9), (5), (2), (1), (1), (1), (1), (1)
Human, Mouse (Murine)
(120), (66), (15), (1)
(85), (41), (21), (2)
(7), (5), (4), (4), (3), (3), (3), (3), (2), (1), (1), (1), (1), (1), (1), (1)
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(94), (47), (21), (20), (14), (11), (10), (9), (7), (5), (4), (2), (2), (2), (2), (2), (1), (1), (1), (1)
Pubmed 1 reference available
Quantity 0.1 mg
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Availability Will be delivered in 6 to 8 Business Days
Immunogen IL-23 antibody was raised against a 16 amino acid peptide from near the amino terminus of human IL-23.
Isotype IgG
Specificity This antibody reacts to Il-23.
Purification Affinity chromatography purified via peptide column
Alternative Name Interleukin-23 alpha / IL23A (IL23A Antibody Abstract)
Background Like interleukin-27 (IL-27), IL-23 is a recently discovered member of the IL-6/IL-12 family of proinflammatory and immunoregulatory cytokines. It exists as a heterodimer composed of the IL-12p40 subunit and a novel p19 subunit. IL-23 is secreted by activated dendritic cells, macrophages, and monocytes (3,4). Its biological activities include enhancing the proliferation of memory T cells and the production of IFN-gamma, IL-12, and TNF-alpha from activated T cells, and can stimulate macrophages to produce TNF-alpha and nitric oxide. It has also been shown to possess potent anti-tumor and anti-metastatic activity in mouse models of cancer, suggesting a potential role for IL-23 in therapeutic treatment of cancer.Synonyms: IL-23 subunit alpha, IL-23p19, Interleukin-23 subunit p19, SGRF
Gene ID 51561
UniProt Q9NPF7
Application Notes ELISA. Western Blot: 1 - 2 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Buffer PBS containing 0.02 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-interleukin 23, alpha subunit p19 (IL23A) (N-Term) antibody (ABIN499998) Immunohistochemistry of IL-23 in mouse pancreas tissue with AP30419PU-N IL-23 antibod...
Western Blotting (WB) image for anti-interleukin 23, alpha subunit p19 (IL23A) (N-Term) antibody (ABIN499998) Western blot analysis of IL-23 in mouse pancreas tissue lysate with AP30419PU-N IL-23...
Background publications Hunter: "New IL-12-family members: IL-23 and IL-27, cytokines with divergent functions." in: Nature reviews. Immunology, Vol. 5, Issue 7, pp. 521-31, 2005 (PubMed).

Catalog No. ABIN499998
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