TLR11 antibody (C-Term, Middle Region)

Catalog No. ABIN500944

This Rabbit Polyclonal antibody specifically detects TLR11 in WB, IF and EIA. It exhibits reactivity toward Mouse.

Quick Overview for TLR11 antibody (C-Term, Middle Region) (ABIN500944)

Target: TLR11 (Tlr11) (Toll-Like Receptor 11 (Tlr11))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TLR11 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Product Details anti-TLR11 Antibody

Binding Specificity: C-Term, Middle Region

Cross-Reactivity (Details): Species reactivity (tested):Mouse

Purification: Ion exchange chromatography

Immunogen: TLR11 antibody was raised against a peptide corresponding to 16 amino acids between the middle and carboxy terminus of mouse TLR11 (GenBank accession no NP_991388).

Isotype: IgG

Application Details

Application Notes: ELISA. Western blot: 0.5 to 2 μg/mL. Imunoflourescence.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store the antibody (in aliquots) at -20 °C.

Target Details for TLR11

Target: TLR11 (Tlr11) (Toll-Like Receptor 11 (Tlr11))

Alternative Name: TLR11

Background: Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses (1-3). These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors (4,5). TLR11 is one of three mouse TLRs that lack a human ortholog (6). It is activated specifically by uropathogenic bacteria, and mice lacking TLR11 showed a much greater susceptability to uropathogenic infections, indicating a potentially important role for TLR11 in preventing infections in the urogenital system (7).Synonyms: Gm287, Toll-like receptor 11

Gene ID: 239081

NCBI Accession: NP_991388

Pathways: Activation of Innate immune Response