Toll-Like Receptor 11 (Tlr11) (C-Term) antibody

Details for Product No. ABIN500942
Antigen
Epitope
C-Term
18
4
3
3
2
2
1
1
1
Reactivity
Mouse (Murine)
38
7
4
3
3
Host
Rabbit
39
2
2
Clonality
Polyclonal
Conjugate
Un-conjugated
3
1
1
1
Application
Enzyme Immunoassay (EIA), Immunofluorescence (IF), Western Blotting (WB)
38
11
8
7
5
3
3
3
1
1
Options
Immunogen TLR11 antibody was raised against a peptide corresponding to 15 amino acids near the carboxy-terminus of mouse TLR11.
Isotype IgG
Specificity This antibody detects TLR11 at C-term.
Cross-Reactivity (Details) Species reactivity (tested):Mouse
Purification Ion exchange chromatography
Antigen
Alternative Name TLR11 (Tlr11 Antibody Abstract)
Background Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses (1-3). These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors (4,5). TLR11 is one of three mouse TLRs that lack a human ortholog (6). It is activated specifically by uropathogenic bacteria, and mice lacking TLR11 showed a much greater susceptability to uropathogenic infections, indicating a potentially important role for TLR11 in preventing infections in the urogenital system (7).Synonyms: Gm287, Toll-like receptor 11
Gene ID 239081
NCBI Accession NP_991388
Pathways Activation of Innate immune Response
Application Notes ELISA. Western blot: 0.5 to 1 μg/mL. Immunoflourescence.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Buffer PBS containing 0.02 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
Supplier Images
Image no. 1 for anti-Toll-Like Receptor 11 (Tlr11) (C-Term) antibody (ABIN500942) Western blot analysis of TLR11 in RAW264.7 cell lysates with AP30895PU-N (A) 0.5 and ...
Image no. 2 for anti-Toll-Like Receptor 11 (Tlr11) (C-Term) antibody (ABIN500942) Immunocytochemical staining of RAW264.7 cells using AP30895PU-N at 2 μg/ml.