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TRAF6 antibody (C-Term)

TRAF6 Reactivity: Human, Mouse, Rat WB, IF, EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN501028
  • Target See all TRAF6 Antibodies
    TRAF6 (TNF Receptor-Associated Factor 6 (TRAF6))
    Binding Specificity
    • 15
    • 9
    • 8
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 57
    • 30
    • 25
    • 15
    • 5
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 56
    • 4
    • 2
    Rabbit
    Clonality
    • 54
    • 8
    Polyclonal
    Conjugate
    • 39
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TRAF6 antibody is un-conjugated
    Application
    • 58
    • 18
    • 14
    • 13
    • 13
    • 11
    • 11
    • 10
    • 7
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    Specificity
    This antibody detects TRAF6 / RNF85 at C-term.
    Cross-Reactivity (Details)
    Species reactivity (tested):Human, mouse, rat
    Purification
    Ion exchange chromatography
    Immunogen
    TRAF6 antibody was raised against a peptide corresponding to 14 amino acids near the C- terminus of human TRAF6.
    Isotype
    IgG
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    Discover our top product TRAF6 Primary Antibody
  • Application Notes
    ELISA. Western blot: 1 to 2 μg/mL. Immunflourescence.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Target
    TRAF6 (TNF Receptor-Associated Factor 6 (TRAF6))
    Alternative Name
    TRAF6 / RNF85 (TRAF6 Products)
    Synonyms
    MGC:3310 antibody, RNF85 antibody, 2310003F17Rik antibody, AI851288 antibody, C630032O20Rik antibody, rnf85 antibody, traf6 antibody, xtraf6 antibody, CG10961 antibody, DTRAF2 antibody, Dmel\\CG10961 antibody, TRAF antibody, TRAF2 antibody, TRAF6 antibody, Traf2 antibody, dTRAF2 antibody, dTRAF6 antibody, dTraf2 antibody, dtraf2 antibody, GB10539 antibody, fi15f02 antibody, wu:fi15f02 antibody, zgc:63704 antibody, TNF receptor associated factor 6 antibody, TNF receptor-associated factor 6 antibody, TNF receptor associated factor 6 L homeolog antibody, TNF-receptor-associated factor 6 antibody, TNF receptor associated factor 6 S homeolog antibody, TRAF6 antibody, Traf6 antibody, traf6.L antibody, traf6 antibody, LOC551819 antibody, traf6.S antibody
    Background
    Signals from the IL-1 receptor (IL-1R)/Toll-like receptor (TLR) and TNF receptor (TNFR) superfamilies are critical for regulating the function of antigen-presenting cells. Signals transduced by these molecules lead to increased expression and activation of transcription factors such as NF-?B (1,2). TNF receptor-associated factor 6 (TRAF6) is unique in that it is a signaling adapter molecule common to both families (3). TRAF6 is important in cytokine production, dendritic cell (DC) maturation, and the T cell stimulatory capacity of DCs in response to TLR and CD40 ligands (4). It can be activated in the IL-1R/TLR signaling pathway by IL-1 receptor-associated kinase 1 (IRAK-1) (5) or by other TLR adaptor molecules such as TRIF (6). Also, it has been shown that TRAF6 can interact directly with TNFR family members CD40 and RANK (7).Synonyms: Interleukin-1 signal transducer, RING finger protein 85, TNF receptor-associated factor 6
    Gene ID
    7189
    NCBI Accession
    NP_004611
    Pathways
    NF-kappaB Signaling, TCR Signaling, TLR Signaling, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Tube Formation, Hepatitis C, Toll-Like Receptors Cascades, Ubiquitin Proteasome Pathway
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