You are viewing an incomplete version of our website. Please click to reload the website as full version.

Tetratricopeptide Repeat Domain 5 (TTC5) (C-Term) antibody

Details for Product No. ABIN501091, Supplier: Log in to see
Antigen
  • TTC5
  • ttc5
  • wu:fi33h05
  • wu:fy81e07
  • zgc:112059
  • Strap
  • 5930437N14
  • AW743060
Epitope
C-Term
19
3
1
1
Reactivity
Human, Mouse (Murine)
22
5
1
1
1
Host
Rabbit
21
1
Clonality
Polyclonal
Conjugate
Un-conjugated
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
21
5
5
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Showcase your results, aid the scientific community, and receive a full refund.

Contribute a validation

Learn more

Available images

Immunogen TTC5 antibody was raised against a 14 amino acid peptide from near the carboxy terminus of human TTC5.
Isotype IgG
Specificity This antibody detects TTC5
Cross-Reactivity (Details) Species reactivity (tested):Human, mouse
Purification Affinity chromatography
Alternative Name TTC5 (TTC5 Antibody Abstract)
Background Tetratricopeptide repeat protein 5 (TTC5) is a member of a diverse group of functionally distinct proteins that are characterized by containing one or more tetratricopeptide repeats (1). Each motif consists of two anti-parallel a-helices such that tandem arrays of TPR motifs generate a right-handed helical structure with an amphipathic channel that may serve to accommodate the complementary region of a target protein. While the exact function of TTC5 remains unclear, it is thought that the TPR motifs serve to mediate protein-protein interactions such as those seen with protein chaperones HSP70 and HSP90 (2) and some proteins involved in cell stress response signaling pathways such as protein phosphatase 5 (3), suggesting that TTC5 may also function via protein-protein interactions mediated by its TPR motifs.Synonyms: TPR repeat protein 5, Tetratricopeptide repeat protein 5
Gene ID 91875
UniProt Q8N0Z6
Research Area Signaling
Pathways
Application Notes ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Buffer PBS containing 0.02 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Tetratricopeptide Repeat Domain 5 (TTC5) (C-Term) antibody (ABIN501091) Immunohistochemistry of TWA1 in rat brain tissue with this product at 2.5 μg/ml.
Western Blotting (WB) image for anti-Tetratricopeptide Repeat Domain 5 (TTC5) (C-Term) antibody (ABIN501091) Western blot analysis of TWA1 in human brain tissue lysate with this product at 1 μg/...
Background publications Blatch, Lässle: "The tetratricopeptide repeat: a structural motif mediating protein-protein interactions." in: BioEssays : news and reviews in molecular, cellular and developmental biology, Vol. 21, Issue 11, pp. 932-9, 1999 (PubMed).