Tetratricopeptide Repeat Domain 5 (TTC5) (C-Term) antibody

Details for Product No. ABIN501091
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Antigen
Synonyms Strap, 5930437N14, AW743060, TTC5, ttc5, wu:fi33h05, wu:fy81e07, zgc:112059
Epitope
C-Term
(14), (3), (1)
Reactivity
Human, Mouse (Murine)
(18), (8), (1), (1), (1)
Host
Rabbit
(19), (1)
Clonality
Polyclonal
Application
ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(20), (8), (6), (1), (1)
Pubmed 1 reference available
Catalog no. ABIN501091
Quantity 0.1 mg
Price
401.50 $   Plus shipping costs $45.00
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  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen TTC5 antibody was raised against a 14 amino acid peptide from near the carboxy terminus of human TTC5.
Isotype IgG
Specificity This antibody detects TTC5
Purification Affinity chromatography
Alternative Name TTC5
Background Tetratricopeptide repeat protein 5 (TTC5) is a member of a diverse group of functionally distinct proteins that are characterized by containing one or more tetratricopeptide repeats (1). Each motif consists of two anti-parallel a-helices such that tandem arrays of TPR motifs generate a right-handed helical structure with an amphipathic channel that may serve to accommodate the complementary region of a target protein. While the exact function of TTC5 remains unclear, it is thought that the TPR motifs serve to mediate protein-protein interactions such as those seen with protein chaperones HSP70 and HSP90 (2) and some proteins involved in cell stress response signaling pathways such as protein phosphatase 5 (3), suggesting that TTC5 may also function via protein-protein interactions mediated by its TPR motifs.
Alternate names: TPR repeat protein 5, Tetratricopeptide repeat protein 5
Gene ID 91875
NCBI Accession Q8N0Z6
Research Area Signaling
Application Notes ELISA. Western blot: 1 - 2 μg/ml. Immunohistochemistry on paraffin sections. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Buffer PBS containing 0.02% sodium azide
Preservative Sodium azide
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
Expiry Date 12 months
Background publications Blatch, Lässle: "The tetratricopeptide repeat: a structural motif mediating protein-protein interactions." in: BioEssays : news and reviews in molecular, cellular and developmental biology, Vol. 21, Issue 11, pp. 932-9, 1999 (PubMed).

Hosts (19), (1)
Reactivities (18), (8), (1), (1), (1)
Applications (20), (8), (6), (1), (1)
Epitopes (14), (3), (1)
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
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