TTC5 antibody (C-Term)
Quick Overview for TTC5 antibody (C-Term) (ABIN1881956)
Target
See all TTC5 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- AA 372-401, C-Term
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Predicted Reactivity
- B
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Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogen
- This TTC5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 372-401 amino acids from the C-terminal region of human TTC5.
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Isotype
- Ig Fraction
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Application Notes
- WB: 1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Expiry Date
- 6 months
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- TTC5 (Tetratricopeptide Repeat Domain 5 (TTC5))
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Alternative Name
- TTC5
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Background
- Adapter protein involved in p53/TP53 response that acts by regulating and mediating the assembly of multi-protein complexes. Required to facilitate the interaction between JMY and p300/EP300 and increase p53/TP53-dependent transcription and apoptosis. Prevents p53/TP53 degradation by MDM2 (By similarity).
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Molecular Weight
- 48928
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NCBI Accession
- NP_612385
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UniProt
- Q8N0Z6
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Pathways
- Chromatin Binding
Target
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