CBX7 antibody (Middle Region)

Catalog No. ABIN501287

The Rabbit Polyclonal anti-CBX7 antibody has been validated for WB. It is suitable to detect CBX7 in samples from Human, Mouse, Rat, Cow, Horse, Rabbit, Guinea Pig and Dog.

Quick Overview for CBX7 antibody (Middle Region) (ABIN501287)

Target: CBX7 (Chromobox Homolog 7 (CBX7))

Reactivity: Human, Mouse, Rat, Cow, Horse, Rabbit, Guinea Pig, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CBX7 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CBX7 Antibody

Binding Specificity: Middle Region

Sequence: ADLAEGPPPW TPALPSSEVT VTDITANSIT VTFREAQAAE GFFRDRSGKF

Predicted Reactivity: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against CBX7. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CBX7

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 251 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CBX7

Target: CBX7 (Chromobox Homolog 7 (CBX7))

Alternative Name: CBX7

Background: CBX7 is involved in maintaining the transcriptionally repressive state of genes. Modifies chromatin, rendering it heritably changed in its expressibility. This protein is regulator of cellular lifespan by maintaining the repression of CDKN2A, but not by inducing telomerase activity.
Alias Symbols: -
Protein Interaction Partner: EED, RNF2, PCGF2, TPR, RING1, RAD17, PHC2, CSNK2B, CSNK2A1, BMI1, CBX7, PCGF3, DCAF7, UBE4A, PCGF1, PCGF5, PCGF6, B3GNT5, CDC42SE1, SRBD1, UCHL5, HMGA1, HDAC2, SUV39H2, HIST3H3, HIST1H4A, HIST1H3A,
Protein Size: 251

Molecular Weight: 28 kDa

Gene ID: 23492

NCBI Accession: NM_175709, NP_783640

UniProt: O95931