C-JUN antibody (Middle Region)

Catalog No. ABIN501642

The Rabbit Polyclonal anti-C-JUN antibody (ABIN501642) specifically detects C-JUN in WB. The antibody is reactive with Human, Mouse, Rat, Cow, Rabbit, Sheep, Dog, Zebrafish (Danio rerio), Guinea Pig, Horse and Goat samples.

Quick Overview for C-JUN antibody (Middle Region) (ABIN501642)

Target: C-JUN (JUN) (Jun Proto-Oncogene (JUN))

Reactivity: Human, Mouse, Rat, Cow, Rabbit, Sheep, Dog, Zebrafish (Danio rerio), Guinea Pig, Horse, Goat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C-JUN antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-C-JUN Antibody

Binding Specificity: Middle Region

Sequence: ERIKAERKRM RNRIAASKCR KRKLERIARL EEKVKTLKAQ NSELASTANM

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 86%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against JUN. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human JUN

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 331 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for C-JUN

Target: C-JUN (JUN) (Jun Proto-Oncogene (JUN))

Alternative Name: JUN

Background: JUN gene is the putative transforming gene of avian sarcoma virus 17. I JUN is highly similar to the viral protein, and interacts directly with specific target DNA sequences to regulate gene expression. JUN gene is intronless and is mapped to 1p32-p31, a chromosomal region involved in both translocations and deletions in human malignancies.This gene is the putative transforming gene of avian sarcoma virus 17. It encodes a protein which is highly similar to the viral protein, and which interacts directly with specific target DNA sequences to regulate gene expression. This gene is intronless and is mapped to 1p32-p31, a chromosomal region involved in both translocations and deletions in human malignancies. This gene is the putative transforming gene of avian sarcoma virus 17. It encodes a protein which is highly similar to the viral protein, and which interacts directly with specific target DNA sequences to regulate gene expression. This gene is intronless and is mapped to 1p32-p31, a chromosomal region involved in both translocations and deletions in human malignancies. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: AP1, c-Jun, AP-1
Protein Interaction Partner: PPP3CA, SP1, HDAC1, GSK3B, FOS, ABL1, MAPK8, RFWD2, CORO7, EP300, STRN4, MAPRE3, CREB3, PRRC2A, MDM2, SMAD2, HSP90AA1, HSPA8, ATF2, APP, APLP2, GOPC, BBS7, ETS1, CREBBP, CASP9, UBC, NCOR1, EPAS1, DDIT3, BATF2, BATF3, BATF, FOSL1, SMARCD3, CEBPG, CEBPE, AT
Protein Size: 331

Molecular Weight: 36 kDa

Gene ID: 3725

NCBI Accession: NM_002228, NP_002219

UniProt: P05412

Pathways: MAPK Signaling, RTK Signaling, WNT Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Myometrial Relaxation and Contraction, Skeletal Muscle Fiber Development, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Autophagy, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling, S100 Proteins