NFE2L1 antibody (Middle Region)

Catalog No. ABIN501657

This anti-NFE2L1 antibody is a Rabbit Polyclonal antibody detecting NFE2L1 in WB. Suitable for Human, Mouse, Rat, Cow, Dog, Rabbit and Guinea Pig.

Quick Overview for NFE2L1 antibody (Middle Region) (ABIN501657)

Target: NFE2L1 (Nuclear Factor (erythroid-Derived 2)-Like 1 (NFE2L1))

Reactivity: Human, Mouse, Rat, Cow, Dog, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NFE2L1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-NFE2L1 Antibody

Binding Specificity: Middle Region

Sequence: FGRLRDENGR PYSPSQYALQ YAGDGSVLLI PRTMADQQAR RQERKPKDRR

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 86%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against NFE2L1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human NFE2L1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 772 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for NFE2L1

Target: NFE2L1 (Nuclear Factor (erythroid-Derived 2)-Like 1 (NFE2L1))

Alternative Name: NFE2L1

Background: NFE2L1 activates erythroid-specific, globin gene expression.This gene encodes a protein that is involved in globin gene expression in erythrocytes. Confusion has occurred in bibliographic databases due to the shared symbol of NRF1 for this gene, NFE2L1, and for 'nuclear respiratory factor 1' which has an official symbol of NRF1. Sequence Note: The RefSeq transcript and protein were derived from transcript and genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-256 DB097304.1 1-256 257-603 DA230932.1 224-570 604-1464 AK090459.1 569-1429 1465-3372 U08853.1 199-2106 3373-4349 AC004477.2 104176-105152 4350-4891 BM983473.1 1-542 c
Alias Symbols: FLJ00380, LCR-F1, NRF1, TCF11
Protein Interaction Partner: UBC, KEAP1, NFE2L1, MAFG, BACH2, CREBZF, MAFF, NFE2L3, FBXW7, GSK3B, CAPN1, CD6, SUMO2, HCFC1, ATF4, MAFK, JUND, JUNB, JUN,
Protein Size: 772

Molecular Weight: 85 kDa

Gene ID: 4779

NCBI Accession: NM_003204, NP_003195

UniProt: Q14494