NFATC1 antibody (Middle Region)

Catalog No. ABIN501732

The Rabbit Polyclonal anti-NFATC1 antibody (ABIN501732) specifically detects NFATC1 in WB and IHC. The antibody is reactive with Human samples.

Quick Overview for NFATC1 antibody (Middle Region) (ABIN501732)

Target: NFATC1 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 1 (NFATC1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NFATC1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-NFATC1 Antibody

Binding Specificity: Middle Region

Sequence: STLMPAAPGV SPKLHDLSPA AYTKGVASPG HCHLGLPQPA GEAPAVQDVP

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against NFATC1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human NFATC1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 825 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for NFATC1

Target: NFATC1 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 1 (NFATC1))

Alternative Name: NFATC1

Background: NFATC1 is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation
Alias Symbols: MGC138448, NF-ATC, NFAT2, NFATc
Protein Interaction Partner: YWHAQ, OGT, PML, GZF1, FOXP3, HDAC4, PIAS1, SUMO1, UBE2I, RPS6KB1, RPS6KA3, HDAC2, HDAC1, HNRNPA1, TUBA1A, KPNB1, HDAC5, KAT2B, EP300, PARP1, HDAC3, PPP3R1, MAPK14, GNB2L1, PRKCA, SPI1, PIM1, EGR2, EGR1,
Protein Size: 825

Molecular Weight: 89 kDa

Gene ID: 4772

NCBI Accession: NM_005093, NP_006153

UniProt: B5B2M8

Pathways: RTK Signaling, WNT Signaling, Fc-epsilon Receptor Signaling Pathway