Polymerase (DNA-Directed), epsilon 4 (p12 Subunit) (POLE4) (N-Term) antibody

Details for Product No. ABIN501810
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Synonyms p12, YHHQ1, 2400007P05Rik, 5830430F06Rik
(2), (1), (1), (1)
Dog (Canine), Cow (Bovine), Human
(10), (6)
(9), (1)
Western Blotting (WB)
(8), (7), (3)
Pubmed 1 reference available
Catalog no. ABIN501810
Quantity 50 µg
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Immunogen Synthetic peptide directed towards the N terminal of human POLE4
Predicted Reactivity Dog : 92 %, Guinea pig : 92 %, Horse : 82 %, Rabbit : 72 %
Characteristics This is a rabbit polyclonal antibody against POLE4. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name POLE4
Background POLE4 is a histone-fold protein that interacts with other histone-fold proteins to bind DNA in a sequence-independent manner. These histone-fold protein dimers combine within larger enzymatic complexes for DNA transcription, replication, and packaging.
Molecular Weight 12 kDa
Gene ID 56655
NCBI Accession NM_019896, NP_063949
UniProt Q9NR33
Application Notes Optimal working dilutions should be determined experimentally by the investigator.

Antigen size: 117 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-Polymerase (DNA-Directed), epsilon 4 (p12 Subunit) (POLE4) (N-Term) antibody WB Suggested Anti-POLE4 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: COLO205 cell lysate
Background publications Hillier, Graves, Fulton et al.: "Generation and annotation of the DNA sequences of human chromosomes 2 and 4...." in: Nature, Vol. 434, Issue 7034, pp. 724-31, 2005 (PubMed).

Hosts (9), (1)
Reactivities (10), (6)
Applications (8), (7), (3)
Epitopes (2), (1), (1), (1)
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