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Cyclin B3 antibody (CCNB3) (C-Term)

Details for Product anti-CCNB3 Antibody No. ABIN501865, Supplier: Login to see New
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Antigen
Synonyms CG5814, Cyc B3, Dmel\\CG5814, anon-WO0118547.414, cycB3, l(3)L6540, ccnb3-a, zgc:153369, MGC154490, NV16541, CCNB3, CYCB3, RGD1564367
Alternatives
Epitope
C-Term
(20), (20), (20), (18), (18), (18), (18), (18), (6), (6), (6), (6), (6), (6), (6), (6), (6), (5), (4), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(80), (64), (45)
Host
Rabbit
(179), (2)
Clonality
Polyclonal
Conjugate
This Cyclin B3 antibody is un-conjugated
(16), (16), (16), (16), (16), (16), (1)
Application
Western Blotting (WB)
(147), (112), (22), (2), (1), (1)
Pubmed 1 reference available
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Quantity 50 μg
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Immunogen Synthetic peptide directed towards the C terminal of human CCNB3
Blocking Peptide Blocking peptide for this product available: ABIN974597
Sequence ISELHPLVRQ LNKLLTFSSY DSLKAVYYKY SHPVFFEVAK IPALDMLKLE
Predicted Reactivity Human : 100 %
Characteristics This is a rabbit polyclonal antibody against CCNB3. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name CCNB3 (CCNB3 Antibody Abstract)
Background CCNB3 belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. Studies of similar genes in chick and Drosophila suggest that this cyclin may associate with CDC2 and CDK2 kinases, and be required for proper spindle reorganization and restoration of the interphase nucleus. Two transcript variants encoding different isoforms have been found for this gene. The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. Studies of similar genes in chick and Drosophila suggest that this cyclin may associate with CDC2 and CDK2 kinases, and be required for proper spindle reorganization and restoration of the interphase nucleus. Two transcript variants encoding different isoforms have been found for this gene.
Molecular Weight 158 kDa
Gene ID 85417
NCBI Accession NM_033031, NP_149020
UniProt Q8WWL7
Pathways Cell Division Cycle
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 1395 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
Western Blotting (WB) image for anti-Cyclin B3 antibody (CCNB3) (C-Term) (ABIN501865) anti-Cyclin B3 (CCNB3) (C-Term) antibody
Background publications Cheng, Kapranov, Drenkow et al.: "Transcriptional maps of 10 human chromosomes at 5-nucleotide resolution." in: Science (New York, N.Y.), Vol. 308, Issue 5725, pp. 1149-54, 2005 (PubMed).

Catalog No. ABIN501865
$289.00
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