EXOSC10 antibody (C-Term)

Catalog No. ABIN501939

This anti-EXOSC10 antibody is a Rabbit Polyclonal antibody detecting EXOSC10 in WB. Suitable for Human, Mouse, Cow, Rabbit, Rat, Dog, Guinea Pig, Horse and Pig. This Primary Antibody has been cited in 1 publication.

Quick Overview for EXOSC10 antibody (C-Term) (ABIN501939)

Target: EXOSC10 (Exosome Component 10 (EXOSC10))

Reactivity: Human, Mouse, Cow, Rabbit, Rat, Dog, Guinea Pig, Horse, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EXOSC10 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-EXOSC10 Antibody

Binding Specificity: C-Term

Sequence: ACKAAAEQAI SVRQQVVLEN AAKKRERATS DPRTTEQKQE KKRLKISKKP

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 92%, Horse: 93%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 100%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against EXOSC10. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region region of human EXOSC10

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 885 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-EXOSC10 antibody (ABIN501939)

van Dijk, Schilders, Pruijn: "Human cell growth requires a functional cytoplasmic exosome, which is involved in various mRNA decay pathways." in: RNA (New York, N.Y.), Vol. 13, Issue 7, pp. 1027-35, (2007) (PubMed).

Target Details for EXOSC10

Target: EXOSC10 (Exosome Component 10 (EXOSC10))

Alternative Name: EXOSC10

Background: EXOSC10 contains 1 HRDC domain and 1 3'-5' exonuclease domain. Antibodies against PM/SCL are found in patients with polymyositis and/or scleroderma.
Alias Symbols: PM-Scl, PM/Scl-100, PMSCL, PMSCL2, RRP6, Rrp6p, p2, p3, p4
Protein Interaction Partner: SUMO2, UBC, SUMO1, RPA3, RPA2, RPA1, NOMO2, EXOSC6, FERMT3, CHPF, LSM2, EXOSC5, FOXRED1, EXOSC4, XRN1, LSM8, B9D1, USP21, UPF2, NOMO1, EXOSC7, DIS3, EXOSC8, IMMT, RUVBL2, EIF3M, TOX4, SSRP1, SKIV2L, LCAT, DXO, ALDH1B1, AICDA, ESR1, EXOSC3, EXOSC9, DIS3L,
Protein Size: 885

Molecular Weight: 101 kDa

Gene ID: 5394

NCBI Accession: NM_001001998, NP_001001998

UniProt: Q01780