Dyskeratosis Congenita 1, Dyskerin (DKC1) (N-Term) antibody

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Antigen
Synonyms
fv62a07, wu:fa28f10, wu:fc87a02, wu:fi24a05, wu:fv62a07, zgc:110395, DKC1, cbf5, dkc, nap57, nola4, xap101, CBF5, DKC, DKCX, NAP57, NOLA4, XAP101, BC068171, Nap57, dyskerin, AtCBF5, AtNAP57, homologue ... show more
fv62a07, wu:fa28f10, wu:fc87a02, wu:fi24a05, wu:fv62a07, zgc:110395, DKC1, cbf5, dkc, nap57, nola4, xap101, CBF5, DKC, DKCX, NAP57, NOLA4, XAP101, BC068171, Nap57, dyskerin, AtCBF5, AtNAP57, homologue of NAP57 show less
Alternatives
Epitope
N-Term
(27), (15), (9), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Reactivity
Chicken, Cow (Bovine), Dog (Canine), Human, Mouse (Murine), Pig (Porcine), Rabbit, Rat (Rattus)
(85), (38), (29), (1), (1), (1), (1), (1), (1)
Host
Rabbit
(61), (20), (4)
Clonality
Polyclonal
Conjugate
Un-conjugated
(4), (4), (4), (3), (3), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(52), (42), (41), (30), (13), (12), (11), (2), (1), (1)
Pubmed 1 reference available
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Quantity 50 μg
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Immunogen Synthetic peptide directed towards the N terminal of human DKC1
Blocking Peptide Blocking peptide for this product available: Dyskeratosis Congenita 1, Dyskerin (DKC1) (N-Term) peptide (ABIN975805)
Sequence EFLIKPESKV AKLDTSQWPL LLKNFDKLNV RTTHYTPLAC GSNPLKREIG
Predicted Reactivity Bovine : 100 %, Dog : 100 %, Guinea pig : 100 %, Horse : 100 %, Human : 100 %, Pig : 100 %, Rabbit : 100 %, Sheep : 100 %, Chicken : 90 %, Mouse : 90 %, Rat : 90 %, Zebrafish : 80 %
Characteristics This is a rabbit polyclonal antibody against DKC1. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name DKC1 (DKC1 Antibody Abstract)
Background This gene is a member of the H/ACA snoRNPs (small nucleolar ribonucleoproteins) gene family. snoRNPs are involved in various aspects of rRNA processing and modification and have been classified into two families: C/D and H/ACA. The H/ACA snoRNPs also incl
Molecular Weight 58 kDa
Gene ID 1736
NCBI Accession NP_001354, NM_001363
UniProt O60832
Research Area Chromatin and Nuclear Signaling, Chromatin Binding Proteins, DNA/RNA
Pathways Telomere Maintenance
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 514 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
Western Blotting (WB) image for anti-Dyskeratosis Congenita 1, Dyskerin (DKC1) (N-Term) antibody (ABIN501957) anti-Dyskeratosis Congenita 1, Dyskerin (DKC1) (N-Term) antibody
Background publications Machado-Pinilla, Sánchez-Pérez, Murguía et al.: "A dyskerin motif reactivates telomerase activity in X-linked dyskeratosis congenita and in telomerase-deficient human cells." in: Blood, Vol. 111, Issue 5, pp. 2606-14, 2008 (PubMed).

Catalog No. ABIN501957
$289.00
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