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Fragile X Mental Retardation, Autosomal Homolog 2 (FXR2) (Middle Region) antibody

Details for Product No. ABIN501987
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Antigen
Synonyms FMR1L2, FXR2P, Fxr2h, id:ibd5046, zgc:56215, zgc:77472
Epitope
Middle Region
(10), (9), (3), (1), (1), (1), (1), (1), (1)
Reactivity
Mouse (Murine), Rat (Rattus), Cow (Bovine), Dog (Canine), Human
(51), (33), (15), (12), (12), (12), (12)
Host
Rabbit
(32), (21)
Clonality
Polyclonal
Conjugate
Un-conjugated
(2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(43), (20), (16), (10), (9), (9), (8), (6), (3), (1)
Pubmed 1 reference available
Quantity 50 µg
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Availability Will be delivered in 2 to 3 Business Days
Catalog No. ABIN501987
289.00 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen Synthetic peptide directed towards the middle region of human FXR2
Sequence RGRRTGGPAYGPSSDVSTASETESEKREEPNRAGPGDRDP PTRGEESRRR
Predicted Reactivity Bovine : 100 %, Dog : 100 %, Human : 100 %, Mouse : 90 %, Pig : 90 %, Rabbit : 90 %, Rat : 90 %, Horse : 80 %
Characteristics This is a rabbit polyclonal antibody against FXR2. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name FXR2
Background FXR2 is a RNA binding protein containing two KH domains and one RCG box, which is similar to FMRP and FXR1. It associates with polyribosomes, predominantly with 60S large ribosomal subunits. This protein may self-associate or interact with FMRP and FXR1. It may have a role in the development of fragile X mental retardation syndrome. The protein encoded by this gene is a RNA binding protein containing two KH domains and one RCG box, which is similar to FMRP and FXR1. It associates with polyribosomes, predominantly with 60S large ribosomal subunits. This encoded protein may self-associate or interact with FMRP and FXR1. It may have a role in the development of fragile X mental retardation syndrome.
Molecular Weight 74 kDa
Gene ID 9513
NCBI Accession NM_004860, NP_004851
UniProt P51116
Research Area Chromatin and Nuclear Signaling, DNA/RNA, Signaling
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 673 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-Fragile X Mental Retardation, Autosomal Homolog 2 (FXR2) (Middle Region) antibody WB Suggested Anti-FXR2 Antibody Titration: 0.2-1 ug/ml
Positive Control: MCF7 cell lysate
Product cited in: Ewing, Chu, Elisma et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry." in: Molecular systems biology, Vol. 3, pp. 89, 2007 (PubMed).

Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN501987
289.00 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Validation Images
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