Solute Carrier Family 22 Member 6 (SLC22A6) (C-Term) antibody

Details for Product No. ABIN502136
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Antigen
Synonyms SLC22A6, OAT1, slc22a6, zgc:77073, Slc22a6, HOAT1, PAHT, ROAT1, NKT, Oat1, Orctl1, mOat1, Paht, Roat1, nkt, oat1, oat1-B, paht, roat1, slc22a6-B
Epitope
C-Term
(15), (7), (4), (4), (2), (1), (1), (1)
Reactivity
Rabbit, Mouse (Murine), Rat (Rattus), Pig (Porcine), Cow (Bovine), Dog (Canine), Zebrafish (Danio rerio), Human
(51), (32), (29), (1), (1), (1), (1), (1)
Host
Rabbit
(63), (2)
Clonality
Polyclonal
Conjugate
Un-conjugated
(3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1)
Application
Western Blotting (WB)
(45), (24), (21), (20), (13), (10), (1), (1)
Pubmed 1 reference available
Quantity 50 μg
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Catalog No. ABIN502136
289.00 $
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Immunogen Synthetic peptide directed towards the C terminal of human SLC22A6
Sequence ETLGQPLPDT VQDLESRWAP TQKEAGIYPR KGKQTRQQQE HQKYMVPLQA
Predicted Reactivity Horse : 100 %, Rat : 100 %, Dog : 90 %, Guinea pig : 80 %
Characteristics This is a rabbit polyclonal antibody against SLC22A6. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name SLC22A6
Background SLC22A6 is involved in the sodium-dependent transport and excretion of organic anions, some of which are potentially toxic. The encoded protein is an integral membrane protein and may be localized to the basolateral membrane.The protein encoded by this gene is involved in the sodium-dependent transport and excretion of organic anions, some of which are potentially toxic. The encoded protein is an integral membrane protein and may be localized to the basolateral membrane. Four transcript variants encoding four different isoforms have been found for this gene.
Molecular Weight 62 kDa
Gene ID 9356
NCBI Accession NM_004790, NP_004781
UniProt Q4U2R8
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 563 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Background publications Windass, Lowes, Wang et al.: "The contribution of organic anion transporters OAT1 and OAT3 to the renal uptake of rosuvastatin." in: The Journal of pharmacology and experimental therapeutics, Vol. 322, Issue 3, pp. 1221-7, 2007 (PubMed).

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