SC5DL antibody (N-Term)

Catalog No. ABIN502559

Product Details anti-SC5DL Antibody

Target: SC5DL (Sterol-C5-Desaturase (SC5DL))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SC5DL antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: NQVRREIKFT VQALPWISIL TVALFLLEIR GYSKLHDDLG EFPYGLFELV

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against SC5DL. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SC5DL

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 299 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SC5DL

Target: SC5DL (Sterol-C5-Desaturase (SC5DL))

Alternative Name: SC5DL (SC5DL Products)

Synonyms: A830037K02 antibody, A830073K23Rik antibody, Sc5dl antibody, ERG3 antibody, S5DES antibody, SC5DL antibody, sc5d antibody, sc5dl antibody, sterol-C5-desaturase antibody, sterol-C5-desaturase L homeolog antibody, Sc5d antibody, SC5D antibody, sc5d.L antibody

Background: SC5DL catalyzes a dehydrogenation to introduce C5-6 double bond into lathosterol.This gene encodes an enzyme of cholesterol biosynthesis. The encoded protein catalyzes the conversion of lathosterol into 7-dehydrocholesterol. Mutations in this gene have been associated with lathosterolosis. Alternatively spliced transcript variants encoding the same protein have been described.
Alias Symbols: ERG3, S5DES, SC5D, SC5DL
Protein Interaction Partner: UBC,
Protein Size: 299

Molecular Weight: 35 kDa

Gene ID: 6309

NCBI Accession: NM_001024956, NP_001020127

UniProt: O75845