LGALS13 antibody

Catalog No. ABIN5026980

Product Details anti-LGALS13 Antibody

Target: LGALS13 (Lectin, Galactoside-Binding, Soluble, 13 (LGALS13))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This LGALS13 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Purification: Protein G Chromatography

Immunogen: A full length human Galectin-13 protein was used as the immunogen for this antibody.

Clone: ABM4E42

Isotype: IgG2b kappa

Application Details

Application Notes: WB: 2-4 μg/mL, IHC: 5 μg/mL

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Target Details for LGALS13

Target: LGALS13 (Lectin, Galactoside-Binding, Soluble, 13 (LGALS13))

Alternative Name: Galectin 13 (LGALS13 Products)

Synonyms: GAL13 antibody, PLAC8 antibody, PP13 antibody, Gal-11 antibody, Gal-13 antibody, Gal11 antibody, gal-13 antibody, galectin 13 antibody, avian beta-defensin 13 antibody, LGALS13 antibody, AvBD13 antibody

Background: Galectin-13 (Gal-13) is a glycan-binding protein that regulates innate and adaptive immune responses. It is predominantly expressed by the syncytiotrophoblast and released from the placenta into the maternal circulation. It has the ability to induce apoptosis of activated T cells in vitro, and divert and kill T cells as well as macrophages in the maternal decidua. Gal-13 with its anti-inflammatory functions plays a role in regulation of maternal immune system, a lack of gal-13 contribute to an imbalance in inflammation processes in the placenta during pregnancy and therefore influences development of gestational diabetes mellitus (GDM). Gal-13 levels are low in the first trimester of pregnancy that confers a higher risk for developing pre-eclampsia later in pregnancy.

Molecular Weight: 32 kDa

Gene ID: 29124

UniProt: Q9UHV8