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RBCK1 antibody (AA 121-333)
RBCK1
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-RBCK1 Antibody
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Target
See all RBCK1 Antibodies
RBCK1
(RanBP-Type and C3HC4-Type Zinc Finger Containing 1 (RBCK1))
Binding Specificity
All epitopes for RBCK1 antibodies
AA 121-333
Reactivity
All reactivities for RBCK1 antibodies
Human
Host
All hosts for RBCK1 antibodies
Rabbit
Clonality
All clonalities for RBCK1 antibodies
Polyclonal
Conjugate
All conjugates for RBCK1 antibodies
This RBCK1 antibody is un-conjugated
Application
All applications for RBCK1 antibodies
Western Blotting (WB)
Purification
Protein A Chromatography
Immunogen
A partial length recombinant HOIL-1L/RBCK1 protein (amino acids 121-333) was used as the immunogen for this antibody.
Isotype
IgG
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Alternatives
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Application Details
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Application Notes
WB: 2-4 μg/mL
Restrictions
For Research Use only
Handling
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Concentration
0.5 mg/mL
Buffer
PBS containing 0.05 % BSA, PH 7.4
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Target Details for RBCK1
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Target
RBCK1
(RanBP-Type and C3HC4-Type Zinc Finger Containing 1 (RBCK1))
Alternative Name
HOIL-1L/RBCK1 (RBCK1 Products )
Synonyms
RBCK1 antibody, C20orf18 antibody, HOIL-1 antibody, HOIL1 antibody, RBCK2 antibody, RNF54 antibody, UBCE7IP3 antibody, XAP3 antibody, XAP4 antibody, ZRANB4 antibody, C20ORF18 antibody, AL033326 antibody, HOIL-1L antibody, UIP28 antibody, Ubce7ip3 antibody, Pkcbpb15 antibody, zgc:91964 antibody, SHANK-associated RH domain interactor antibody, RANBP2-type and C3HC4-type zinc finger containing 1 antibody, ranBP-type and C3HC4-type zinc finger-containing protein 1 antibody, RanBP-type and C3HC4-type zinc finger containing 1 antibody, SHARPIN antibody, RBCK1 antibody, LOC100411512 antibody, Rbck1 antibody, rbck1 antibody
Background
RBCK1 (RanBP-type and C3HC4-type zinc finger containing 1) is a transcription factor belonging to the RING-IBR protein family. It shuttles between the nucleus and cytoplasm, possessing both the nuclear export and localization signals within its amino acid sequence. RBCK1 deficiency causes polyglucosan storage myopathy associated with progressive muscle weakness and cardiomyopathy. RBCK1 negatively regulates the cellular antiviral response. RBCK1 regulates cell cycle progression and proliferation of ERalpha (estrogen receptor alpha)-positive breast cancer cells by supporting transcription of ERalpha and cyclin B1.
Molecular Weight
58 kDa
Gene ID
10616
UniProt
Q9BYM8
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