LRRC8B antibody (Middle Region)

Catalog No. ABIN502806

Cited in 1 publication. The Rabbit Polyclonal anti-LRRC8B antibody (ABIN502806) specifically detects LRRC8B in WB and IHC. The antibody is reactive with Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse and Rabbit samples.

Quick Overview for LRRC8B antibody (Middle Region) (ABIN502806)

Target: LRRC8B (Leucine Rich Repeat Containing 8 Family, Member B (LRRC8B))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LRRC8B antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-LRRC8B Antibody

Binding Specificity: Middle Region

Sequence: TLYLKSSLSR IPQVVTDLLP SLQKLSLDNE GSKLVVLNNL KKMVNLKSLE

Predicted Reactivity: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against LRRC8B. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human LRRC8B

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 803 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-LRRC8B antibody (ABIN502806)

Kubota, Kim, Sawada, Tokimasa, Fujisaki, Matsuda-Hashii, Ozono, Hara: "LRRC8 involved in B cell development belongs to a novel family of leucine-rich repeat proteins." in: FEBS letters, Vol. 564, Issue 1-2, pp. 147-52, (2004) (PubMed).

Target Details for LRRC8B

Target: LRRC8B (Leucine Rich Repeat Containing 8 Family, Member B (LRRC8B))

Alternative Name: LRRC8B

Background: The exact function of LRRC8B remains unknown.
Alias Symbols: KIAA0231, MGC42220, TA-LRRP, TALRRP
Protein Interaction Partner: CUL3,
Protein Size: 803

Molecular Weight: 92 kDa

Gene ID: 23507

NCBI Accession: NM_015350, NP_056165

UniProt: Q6P9F7