TRAPPC2 antibody (Middle Region)

Catalog No. ABIN503168

Product Details anti-TRAPPC2 Antibody

Target: TRAPPC2 (Trafficking Protein Particle Complex 2 (TRAPPC2))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRAPPC2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: RQEDGIKNFF TDVYDLYIKF SMNPFYEPNS PIRSSAFDRK VQFLGKKHLL

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against TRAPPC2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TRAPPC2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 140 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TRAPPC2

Target: TRAPPC2 (Trafficking Protein Particle Complex 2 (TRAPPC2))

Alternative Name: TRAPPC2 (TRAPPC2 Products)

Synonyms: MIP2A antibody, SEDL antibody, SEDT antibody, TRAPPC2P1 antibody, TRS20 antibody, ZNF547L antibody, hYP38334 antibody, 1110066L09Rik antibody, 1810064C02Rik antibody, AW496358 antibody, MIP-2A antibody, Sedl antibody, RGD1306925 antibody, trafficking protein particle complex 2 antibody, trafficking protein particle complex 2 S homeolog antibody, trappc2 antibody, TRAPPC2 antibody, Trappc2 antibody, trappc2.S antibody

Background: TRAPPC2 prevents MBP1-mediated transcriptional repression and antagonizes MBP1-mediated cell death. TRAPPC2 may play a role in vesicular transport from endoplasmic reticulum to Golgi.The protein encoded by this gene is thought to be part of a large multisubunit complex involved in the targeting and fusion of endoplasmic reticulum-to-Golgi transport vesicles with their acceptor compartment. In addition, the encoded protein can bind MBP1 and block its transcriptional repression capability. Mutations in this gene are a cause of spondyloepiphyseal dysplasia tarda (SEDT). A processed pseudogene of this gene is located on chromosome 19, and other pseuodogenes are found on chromosomes 8 and Y. Alternatively spliced transcript variants encoding distinct isoforms or having different 5' UTRs, have been found for this gene.
Alias Symbols: MIP-2A, SEDL, SEDT, TRS20, ZNF547L, hYP38334, MIP2A, TRAPPC2P1
Protein Interaction Partner: TRAPPC3L, TRAPPC5, TRAPPC6B, TRAPPC9, TRAPPC6A, TRAPPC11, TRAPPC4, TRAPPC12, TRAPPC3, TRAPPC8, TRAPPC10, ELAVL1, UBC, JOSD2, CLIC1, CLIC2, ENO1,
Protein Size: 140

Molecular Weight: 16 kDa

Gene ID: 6399

NCBI Accession: NM_014563, NP_055378

UniProt: O14582