EIF2B1 antibody (C-Term)

Catalog No. ABIN503287

This Rabbit Polyclonal antibody specifically detects EIF2B1 in WB and IHC. It exhibits reactivity toward Human, Mouse, Rat, Dog, Pig, Rabbit, Cow and Horse.

Quick Overview for EIF2B1 antibody (C-Term) (ABIN503287)

Target: EIF2B1 (Eukaryotic Translation Initiation Factor 2B, Subunit 1 Alpha, 26kDa (EIF2B1))

Reactivity: Human, Mouse, Rat, Dog, Pig, Rabbit, Cow, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EIF2B1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-EIF2B1 Antibody

Binding Specificity: C-Term

Sequence: ADTLKVAQTG QDLKEEHPWV DYTAPSLITL LFTDLGVLTP SAVSDELIKL

Predicted Reactivity: Cow: 79%, Dog: 79%, Horse: 93%, Human: 100%, Mouse: 86%, Pig: 79%, Rabbit: 79%, Rat: 79%

Characteristics: This is a rabbit polyclonal antibody against EIF2B1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human EIF2B1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 305 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for EIF2B1

Target: EIF2B1 (Eukaryotic Translation Initiation Factor 2B, Subunit 1 Alpha, 26kDa (EIF2B1))

Alternative Name: EIF2B1

Background: EIF2B1 belongs to the EIF-2B alpha/beta/delta subunits family. It catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. Defects in EIF2B1 are a cause of leukoencephalopathy with vanishing white matter (VWM).
Alias Symbols: EIF-2B, EIF-2Balpha, EIF2B, EIF2BA, MGC117409, MGC125868, MGC125869
Protein Interaction Partner: RD3, WDYHV1, GORASP2, EIF2B1, UBC, GCD2, GCD6, EIF2B2, STK11, DCC, MRPL4, EIF2S2, EIF2S1, ARL4D, CREBBP, ADRB2, ADRA2B, ADRA2C, ADRA2A, EIF2B5, DCD, PDIA4, EIF2B3, HNRNPL, ARHGDIA,
Protein Size: 305

Molecular Weight: 34 kDa

Gene ID: 1967

NCBI Accession: NM_001414, NP_001405

UniProt: Q14232

Pathways: Methionine Biosynthetic Process