GGN antibody (N-Term)

Catalog No. ABIN503425

This Rabbit Polyclonal antibody specifically detects GGN in WB. It exhibits reactivity toward Human, Rat, Mouse, Cow, Dog, Guinea Pig and Rabbit.

Quick Overview for GGN antibody (N-Term) (ABIN503425)

Target: GGN (Gametogenetin (GGN))

Reactivity: Human, Rat, Mouse, Cow, Dog, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GGN antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GGN Antibody

Binding Specificity: N-Term

Sequence: GPSKWQKPAG TPVPRIRRLL EASHRGQGDP PSLRPLKPPP PPRQLSVKDT

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against GGN. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GGN

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 652 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for GGN

Target: GGN (Gametogenetin (GGN))

Alternative Name: GGN

Background: GGN may be involved in spermatogenesis.This gene is a germ cell-specific gene that encodes proteins that interact with POG (proliferation of germ cells). Alternatively spliced transcript variants of a similar mouse gene encode at least three different proteins, namely gametogenetin protein 1a, gametogenetin protein 2, and gametogenetin protein 3, which show a perinuclear, cytoplasmic, and nucleolar localization, respectively. These proteins regulate the localization of POG and may play a role in spermatogenesis.
Alias Symbols: FLJ35713, MGC33369
Protein Interaction Partner: KRT40, ECT2, BRCA1, OAZ3, GGNBP2, GGN, FANCL,
Protein Size: 652

Molecular Weight: 67 kDa

Gene ID: 199720

NCBI Accession: NM_152657, NP_689870

UniProt: Q86UU5