Epidermal Growth Factor Receptor Pathway Substrate 8 (EPS8) (Middle Region) antibody

Details for Product No. ABIN503558
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Antigen
Synonyms MGC81285, MGC146320, AW261790
Epitope
Middle Region
(9), (3), (3), (2), (1), (1), (1)
Reactivity
Mouse (Murine), Human
(35), (17), (15), (12), (12), (12), (12)
Host
Rabbit
(31), (5), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(23), (13), (12), (11), (10), (1), (1), (1)
Pubmed 1 reference available
Quantity 50 μg
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Catalog No. ABIN503558
289.00 $
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Immunogen Synthetic peptide directed towards the middle region of human EPS8
Sequence VSKVPANITR QNSSSSDSGG SIVRDSQRHK QLPVDRRKSQ MEEVQDELIH
Predicted Reactivity Bovine : 100 %, Human : 100 %, Mouse : 100 %, Pig : 100 %, Dog : 90 %, Horse : 90 %, Rabbit : 90 %, Rat : 80 %, Chicken : 80 %
Characteristics This is a rabbit polyclonal antibody against EPS8. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name EPS8
Background This gene encodes a member of the EPS8 family. This protein contains one PH domain and one SH3 domain. It functions as part of the EGFR pathway, though its exact role has not been determined. Highly similar proteins in other organisms are involved in the
Molecular Weight 92 kDa
Gene ID 2059
NCBI Accession NP_004438, NM_004447
UniProt Q12929
Research Area Cancer, Growth Factors
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 822 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-Epidermal Growth Factor Receptor Pathway Substrate 8 (EPS8) (Middle Region) antibody WB Suggested Anti-EPS8 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: ACHN cell lysate
anti-Epidermal Growth Factor Receptor Pathway Substrate 8 (EPS8) (Middle Region) antibody (2) WB Suggested Anti-EPS8
Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.2500
Positive Control: ACHN cell lysate
EPS8 is supported by BioGPS gene expression data to be expressed in ACHN
Background publications Welsch, Endlich, Giese et al.: "Eps8 is increased in pancreatic cancer and required for dynamic actin-based cell protrusions and intercellular cytoskeletal organization." in: Cancer letters, Vol. 255, Issue 2, pp. 205-18, 2007 (PubMed).

Validation Images
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