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Details for Product No. ABIN503558

Epidermal Growth Factor Receptor Pathway Substrate 8 (EPS8) (Middle Region) antibody

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Antigen
Synonyms AW261790, MGC81285, MGC146320
Epitope
»Alternatives Middle Region
Reactivity
»Alternatives Mouse (Murine), Human
Host
»Alternatives Rabbit
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB)
Pubmed 1 reference available
Catalog no. ABIN503558
Quantity 50 µg
Price
289.00 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen The immunogen for anti-EPS8 antibody: synthetic peptide directed towards the middle region of human EPS8
Sequence VSKVPANITRQNSSSSDSGGSIVRDSQRHKQLPVDRRKSQ MEEVQDELIH
Predicted Reactivity Bovine : 100%, Human : 100%, Mouse : 100%, Pig : 100%, Dog : 92%, Horse : 92%, Rabbit : 92%, Rat : 85%, Chicken : 84%
Characteristics This is a rabbit polyclonal antibody against EPS8. It was validated on Western Blot using a cell lysate as a positive control. We strive to provide antibodies covering each member of a whole protein family of your interest.
Purification Affinity Purified
Alternative Name EPS8
Background This gene encodes a member of the EPS8 family. This protein contains one PH domain and one SH3 domain. It functions as part of the EGFR pathway, though its exact role has not been determined. Highly similar proteins in other organisms are involved in the
Molecular Weight 92kDa
Gene ID 2059
NCBI Accession NP_004438, NM_004447
UniProt Q12929
Research Area Cancer, Growth Factors
Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water
Concentration 1mg/mL
Buffer Final anti-EPS8 antibody concentration is 1 mg/mL in PBS buffer.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Background publications Welsch, Endlich, Giese et al.: "Eps8 is increased in pancreatic cancer and required for dynamic actin-based cell protrusions and intercellular cytoskeletal organization." in: Cancer letters, Vol. 255, Issue 2, pp. 205-18, 2007 (PubMed).

Alternatives for antigen "Epidermal Growth Factor Receptor Pathway Substrate 8 (EPS8)", type "Antibodies"
Hosts (26), (5), (1)
Reactivities (30), (17), (16), (13), (13), (13), (12), (1), (1), (1)
Applications (17), (13), (10), (10), (4), (1), (1), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (4), (2), (2), (1), (1), (1)
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