»
Antibodies
»
anti-SUMO1/sentrin Specific Peptidase 5 (SENP5) antibody
SUMO1/sentrin Specific Peptidase 5 (SENP5) antibody
| Antigen |
|
| Synonyms |
FLJ42398, MGC27076, DKFZp564O1016 |
| Clonality |
Polyclonal |
|
Host
|
|
|
Reactivity
|
Alternatives Dog (Canine), Human, Mouse (Murine), Rat (Rattus)
|
|
Conjugate
|
Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE-Cy3 (1), PE-Cy5 (1), PE-Cy5.5 (1), PE-Cy7 (1)
|
|
Application
|
|
| Catalog no. |
ABIN503708 |
| Quantity |
50 µg |
| Price |
317.90 $ Plus shipping costs $45.00
|
|
Bulk discount
|
| Shipping to |
|
| Availability |
Will be delivered in 2 to 3 Business Days |
|
Alternative name
|
SENP5
|
|
Gene ID
|
SENP5
|
|
UniProt
|
Q96HI0
|
|
Immunogen
|
The immunogen for anti-SENP5 antibody: synthetic peptide directed towards the middle region of human SENP5
|
|
Sequence
|
LSGFLDEVMKKYGSLVPLSEKEVLGRLKDVFNEDFSNRKP FINREITNYR
|
|
Cross-Reactivity
|
Dog (Canine), Human, Mouse (Murine), Rat (Rattus)
|
|
Format
|
Lyophilized
|
|
Reconstitution
|
Add 50 µl of distilled water. Final anti-SENP5 antibody concentration is 1 mg/ml.
|
|
Description
|
The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1, MIM 601912) is required for numerous biologic processes. SUMO-specific proteases, such as SENP5, are responsible for the initial processing of SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also have isopeptidase activity for the removal of SUMO from high molecular mass SUMO conjugates.
|
|
Characteristics
|
Antigen Size: 755 amino acids
|
|
Molecular Weight
|
87kDa
|
|
Application Notes
|
WB Suggested Anti-SENP5 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positive Control: 293T cell lysate.
|
|
Purification
|
Affinity Purified
|
|
Buffer
|
PBS
|
|
Storage (Long Term)
|
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
|
|
Storage (Short Term)
|
Any unfrozen and/or unused material can be stored at 4°C for short term use (< 1 week), and should not be re-frozen.
|
|
Research Area
|
Proteolysis / Ubiquitin
|
|
Restrictions
|
For Research Use only
|
|
Product
|
Gong, Yeh: "Characterization of a family of nucleolar SUMO-specific proteases with preference for SUMO-2 or SUMO-3." in: The Journal of biological chemistry, Vol. 281, Issue 23, pp. 15869-77, 2006 (PubMed).
|
Alternatives for antigen "SUMO1/sentrin Specific Peptidase 5 (SENP5)", type "Antibodies"
|
Hosts
|
Rabbit (36)
|
|
Reactivities
|
Human (34), Mouse (Murine) (23), Rat (Rattus) (22), Cow (Bovine) (18), Dog (Canine) (18), Horse (Equine) (18), Pig (Porcine) (18), Rabbit (18)
|
|
Applications
|
Western Blotting (WB) (20), ELISA (15), Immunofluorescence (IF) (15), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (7), Immunohistochemistry (IHC) (6), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Immunoelectron Microscopy (IEM) (1)
|
|
Conjugates
|
Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE-Cy3 (1), PE-Cy5 (1), PE-Cy5.5 (1), PE-Cy7 (1)
|
|
Epitopes
|
C-Term (5), AA 229-246 (2), C-Term,AA 717-747 (1), Internal Region (1)
|