SENP5 antibody (AA 651-700)

Catalog No. ABIN1533439

The Rabbit Polyclonal anti-SENP5 antibody is suitable to detect SENP5 in samples from Human, Mouse and Monkey. It has been validated for WB, IHC, ELISA and IF.

Quick Overview for SENP5 antibody (AA 651-700) (ABIN1533439)

Target: SENP5 (SUMO1/sentrin Specific Peptidase 5 (SENP5))

Reactivity: Human, Mouse, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SENP5 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-SENP5 Antibody

Binding Specificity: AA 651-700

Purpose: SENP5 Antibody

Specificity: SENP5 Polyclonal Antibody detects endogenous levels of SENP5 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human SENP5. AA range:651-700

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for SENP5

Target: SENP5 (SUMO1/sentrin Specific Peptidase 5 (SENP5))

Alternative Name: SENP5

Background:

Synonyms: SENP5, FKSG45, Sentrin-specific protease 5, Sentrin/SUMO-specific protease SENP5

Background: The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1, MIM 601912) is required for numerous biologic processes. SUMO-specific proteases, such as SENP5, are responsible for the initial processing of SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also have isopeptidase activity for the removal of SUMO from high molecular mass SUMO conjugates (Di Bacco et al., 2006 [PubMed 16738315]).[supplied by OMIM, Jun 2009],

Gene Name: SENP5

Protein Name: Sentrin-specific protease 5

Molecular Weight: 86 kDa

Gene ID: 205564

OMIM: 612845

UniProt: Q96HI0