Phosphatidic Acid Phosphatase Type 2 Domain Containing 2 (PPAPDC2) (N-Term) antibody

Details for Product No. ABIN503814
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Antigen
Synonyms PPAPDC2, PDP1, PSDP, bA6J24.6, 4932443D16Rik
Epitope
N-Term
(12), (9), (7), (1), (1)
Reactivity
Human
(26), (10), (10), (1)
Host
Rabbit
(26)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(26), (16), (4)
Pubmed 1 reference available
Quantity 50 µg
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Catalog No. ABIN503814
289.00 $
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Immunogen Synthetic peptide directed towards the N terminal of human PPAPDC2
Sequence FPLAAAGPSQ SPAPPLPEED RMDLNPSFLG IALRSLLAID LWLSKKLGVC
Predicted Reactivity Human :100 %,  
Characteristics This is a rabbit polyclonal antibody against PPAPDC2. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name PPAPDC2
Background PPAPDC2 is the phosphatase that dephosphorylates presqualene diphosphate (PSDP) into presqualene monophosphate (PSMP), suggesting that it may be indirectly involved in innate immunity. PSDP is a bioactive lipid that rapidly remodels to presqualene monophosphate PSMP upon cell activation. PPAPDC2 displays diphosphate phosphatase activity with a substrate preference for PSDP > FDP > phosphatidic acid.
Molecular Weight 32 kDa
Gene ID 403313
NCBI Accession NM_203453, NP_982278
UniProt Q8IY26
Research Area Signaling, Metabolism
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 295 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-Phosphatidic Acid Phosphatase Type 2 Domain Containing 2 (PPAPDC2) (N-Term) antibody WB Suggested Anti-PPAPDC2 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: Hela cell lysate
Background publications Olsen, Blagoev, Gnad et al.: "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks." in: Cell, Vol. 127, Issue 3, pp. 635-48, 2006 (PubMed).

Validation Images
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