ASAH1 antibody (Middle Region)

Catalog No. ABIN504351

This anti-ASAH1 antibody is a Rabbit Polyclonal antibody detecting ASAH1 in WB and IHC. Suitable for Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse and Pig.

Quick Overview for ASAH1 antibody (Middle Region) (ABIN504351)

Target: ASAH1 (N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1 (ASAH1))

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ASAH1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-ASAH1 Antibody

Binding Specificity: Middle Region

Sequence: QSGEGCVITR DRKESLDVYE LDAKQGRWYV VQTNYDRWKH PFFLDDRRTP

Predicted Reactivity: Cow: 85%, Dog: 85%, Guinea Pig: 92%, Horse: 92%, Human: 100%, Mouse: 92%, Pig: 100%, Rat: 92%

Characteristics: This is a rabbit polyclonal antibody against ASAH1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ASAH1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 395 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ASAH1

Target: ASAH1 (N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1 (ASAH1))

Alternative Name: ASAH1

Background: This gene encodes a heterodimeric protein consisting of a nonglycosylated alpha subunit and a glycosylated beta subunit that is cleaved to the mature enzyme posttranslationally. The encoded protein catalyzes the synthesis and degradation of ceramide into
Alias Symbols: AC, ASAH, FLJ21558, FLJ22079, PHP, PHP32, ACDase
Protein Interaction Partner: SRPK1, CAMK1D, FBXO6, UBC, PSMA3, Bub1b, TSC22D1, SETDB1, SMPD1,
Protein Size: 395

Molecular Weight: 14 kDa

Gene ID: 427

NCBI Accession: NM_177924, NP_808592

UniProt: Q13510